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PMID: 19812586 Published · ppublish English Journal Article Research Support, N.I.H., Extramural

Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age.

Nowell L, Moran C, Smith PB, Seed P, Alexander BD, Cotten CM, Wiener JS, Benjamin DK

Abstract

Our aim was to determine the incidence of anatomical abnormalities after a urinary tract infection (UTI) in infants <2 months of age hospitalized in the neonatal intensive care unit (NICU). This was a retrospective, single-center cohort study of infants <2 months of age in the NICU with a UTI and documented renal imaging. We identified 141 infants with UTIs. The mean gestational age and birth weight were 28 weeks and 1254 g, respectively. The most commonly identified pathogen was coagulase-negative Staphylococcus (28%, 44 of 156). A major abnormality was found on at least one imaging study for 4% (5 of 118) of infants. Major abnormalities were noted on 4% (5 of 114) of renal ultrasounds and 2% (2 of 82) of voiding cystourethrography examinations. Among infants in the NICU <2 months of age at the time of a UTI, the prevalence of major anatomical abnormalities is <5%.

MeSH Terms
Academic Medical Centers/statistics & numerical data Female Humans Hydronephrosis/complications,diagnostic imaging,epidemiology Infant Infant, Newborn Intensive Care Units, Neonatal/statistics & numerical data Male North Carolina/epidemiology Prevalence Ultrasonography Urinary Tract Infections/complications Urogenital Abnormalities/complications,diagnostic imaging,epidemiology
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Nowell L
Duke University School of Medicine, Durham, NC, USA.
Moran C
Smith P B
Seed P
Alexander B D
Cotten C M
Wiener J S
Benjamin D K
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Article Info
Journal
Journal of perinatology : official journal of the California Perinatal Association
Abbr.
J Perinatol
ISSN
1476-5543
Published
2010-04-00
Epub
2009-00-08
Pages
281-5
Language
English
Region
United States
NLM ID
8501884
PMCID
PMC2847635
Subset
IM
Grants
NICHD NIH HHS · K12 HD043494 · United States
NICHD NIH HHS · 1K23HD060040-01 · United States
NICHD NIH HHS · HD-044799-03 · United States
NICHD NIH HHS · K23 HD060040-01 · United States
NICHD NIH HHS · K23 HD060040 · United States
NICHD NIH HHS · K24 HD058735 · United States
NICHD NIH HHS · K23 HD044799-03 · United States
NICHD NIH HHS · K23 HD044799 · United States
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