O-antigen variation in Salmonella spp.: rfb gene clusters of three strains.

Journal of bacteriology ·Vol. 170 ·No. 1 ·1988-01-00 ·Pages 103-7

Verma NK, Quigley NB, Reeves PR

Abstract

The O antigens of Salmonella serogroups A, B, and D differ structurally in their side-chain sugar residue. These genes encoding O-antigen biosynthesis are clustered in the rfb operon. We report here the molecular cloning and analysis of the rfb operons of Salmonella paratyphi A (serogroup A) and S. typhi (serogroup D). The regions of DNA nonhomology between the rfb operons of these serogroup A, B, and D representatives are identified, and the evolutionary derivation of serogroup A from a serogroup D progenitor is discussed.

MeSH Terms

Antigenic Variation Antigens, Bacterial/genetics Chromosome Mapping Cloning, Molecular Cosmids DNA Restriction Enzymes DNA, Bacterial/genetics,ultrastructure Genes, Bacterial Microscopy, Electron Nucleic Acid Hybridization O Antigens Operon Salmonella/genetics,immunology Salmonella paratyphi A/genetics,immunology Salmonella typhi/genetics,immunology Salmonella typhimurium/genetics,immunology Sequence Homology, Nucleic Acid

Chemicals

Antigens, Bacterial DNA, Bacterial O Antigens DNA Restriction Enzymes

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Verma N K

Department of Microbiology, University of Sydney, New South Wales, Australia.

Quigley N B

Reeves P R

References (14)

14 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.170.1.103-107.1988

Published

1988-01-00

Pages

103-7

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC210612

Subset

External Links

PubMed source DOI: 10.1128/jb.170.1.103-107.1988 PMC Full Text View journal details

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O-antigen variation in Salmonella spp.: rfb gene clusters of three strains.

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