Mutants of group D1 Salmonella carrying the somatic antigen of group A organisms: isolation and serological characterization.

Journal of bacteriology ·Vol. 117 ·No. 1 ·1974-01-00 ·Pages 8-12

Uchida T, Matsumoto T, Sasaki T

Abstract

O antigen mutants were obtained from Salmonella durban, a group D(1) organism, by treatment with N-methyl-N'-nitro-N-nitrosoguanidine. Serological studies demonstrated that the mutants lost the O-9 antigen factor of the parent organism but acquired the O-2 factor specific to group A Salmonella. Lipopolysaccharides of the mutant strains contained paratose which determines the specificity of O-2 factor. Tyvelose, present in the wild-type lipopolysaccharide, was not found in the mutants. H antigens and other biological characteristics of the mutant strains were the same as those of the wild-type organism. The present finding implies that group A Salmonella species might be derived from group D(1) organisms.

MeSH Terms

Agglutination Tests Antigens, Bacterial/analysis,isolation & purification Chromatography, Paper Hexoses/analysis Lipopolysaccharides/analysis,isolation & purification Mutagens Mutation Nitrosoguanidines Polysaccharides, Bacterial/analysis,isolation & purification Salmonella/classification,immunology Salmonella paratyphi A/immunology Salmonella typhi/immunology Salmonella typhimurium/immunology Serotyping Species Specificity

Chemicals

Antigens, Bacterial Hexoses Lipopolysaccharides Mutagens Nitrosoguanidines Polysaccharides, Bacterial

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Uchida T

Matsumoto T

Sasaki T

References (11)

11 references, click to expand

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Mutants of group D1 Salmonella carrying the somatic antigen of group A organisms: evidence for the lack of cytidine diphosphate paratose-2-epimerase activity.
J Bacteriol. 1974 Jan;117(1):13-8 PMID: 4808896
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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.117.1.8-12.1974

Published

1974-01-00

Pages

8-12

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC246518

Subset

External Links

PubMed source DOI: 10.1128/jb.117.1.8-12.1974 PMC Full Text View journal details

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Mutants of group D1 Salmonella carrying the somatic antigen of group A organisms: isolation and serological characterization.

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