Abstract
A sequential pattern of interactions of trans-acting factors in rat liver with the phosphoenolpyruvate carboxykinase promoter during late development was observed. A liver-enriched factor, possibly AF1, interacted with the promoter in fetal liver, whereas a factor with the characteristics of C/EBP bound the promoter after birth with the onset of the gene expression.
MeSH Terms
Age Factors
Animals
Base Sequence
Gene Expression Regulation
Liver/growth & development,physiology
Molecular Sequence Data
Nuclear Proteins/physiology
Phosphoenolpyruvate Carboxykinase (GTP)/genetics
Promoter Regions, Genetic
Rats
Regulatory Sequences, Nucleic Acid
Transcription Factors/physiology
Transcription, Genetic
Chemicals
Nuclear Proteins
Transcription Factors
Phosphoenolpyruvate Carboxykinase (GTP)
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Trus M
Department of Developmental Biochemistry, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Benvenisty N
Cohen H
Reshef L
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