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PMID: 2325658 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Developmentally regulated interactions of liver nuclear factors with the rat phosphoenolpyruvate carboxykinase promoter.

Molecular and cellular biology ·Vol. 10 ·No. 5 ·1990-05-00 ·Pages 2418-22

Trus M, Benvenisty N, Cohen H, Reshef L

Abstract

A sequential pattern of interactions of trans-acting factors in rat liver with the phosphoenolpyruvate carboxykinase promoter during late development was observed. A liver-enriched factor, possibly AF1, interacted with the promoter in fetal liver, whereas a factor with the characteristics of C/EBP bound the promoter after birth with the onset of the gene expression.

MeSH Terms
Age Factors Animals Base Sequence Gene Expression Regulation Liver/growth & development,physiology Molecular Sequence Data Nuclear Proteins/physiology Phosphoenolpyruvate Carboxykinase (GTP)/genetics Promoter Regions, Genetic Rats Regulatory Sequences, Nucleic Acid Transcription Factors/physiology Transcription, Genetic
Chemicals
Nuclear Proteins Transcription Factors Phosphoenolpyruvate Carboxykinase (GTP)
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Trus M
Department of Developmental Biochemistry, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Benvenisty N
Cohen H
Reshef L
References (25)
25 references, click to expand
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Article Info
Journal
Molecular and cellular biology
Abbr.
Mol Cell Biol
ISSN
0270-7306
Published
1990-05-00
Pages
2418-22
Language
English
Region
United States
NLM ID
8109087
PMCID
PMC360591
Subset
IM
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