Learning in motion: pericytes instruct migrating innate leukocytes.

Nature immunology ·Vol. 14 ·No. 1 ·2013-01-00 ·Pages 14-5

Alon R, Nourshargh S

Abstract

暂无摘要

MeSH Terms

Humans Intercellular Adhesion Molecule-1/metabolism Intramolecular Oxidoreductases/metabolism Leukocytes/immunology Macrophage Migration-Inhibitory Factors/metabolism Pericytes/immunology Receptors, Pattern Recognition/immunology

Chemicals

Macrophage Migration-Inhibitory Factors Receptors, Pattern Recognition Intercellular Adhesion Molecule-1 Intramolecular Oxidoreductases MIF protein, human

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Alon Ronen

Nourshargh Sussan

References (10)

10 references, click to expand

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Origin and physiological roles of inflammation.
Nature. 2008 Jul 24;454(7203):428-35 PMID: 18650913
Macrophage migration inhibitory factor: a regulator of innate immunity.
Nat Rev Immunol. 2003 Oct;3(10):791-800 PMID: 14502271
Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse.
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Intravascular danger signals guide neutrophils to sites of sterile inflammation.
Science. 2010 Oct 15;330(6002):362-6 PMID: 20947763
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
J Exp Med. 2012 Jun 4;209(6):1219-34 PMID: 22615129
MIF signal transduction initiated by binding to CD74.
J Exp Med. 2003 Jun 2;197(11):1467-76 PMID: 12782713
Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs.
Nat Immunol. 2013 Jan;14(1):41-51 PMID: 23179077
LTB4 is a signal-relay molecule during neutrophil chemotaxis.
Dev Cell. 2012 May 15;22(5):1079-91 PMID: 22542839
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Article Info

Journal

Nature immunology

Abbr.

Nat Immunol

ISSN

1529-2916

DOI

10.1038/ni.2489

Published

2013-01-00

Pages

14-5

Language

English

Region

United States

NLM ID

100941354

Subset

Corrections

CommentOn

PMID: 23179077

External Links

PubMed source DOI: 10.1038/ni.2489 View journal details

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Learning in motion: pericytes instruct migrating innate leukocytes.

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