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PMID: 23179023 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions.

Nature genetics ·Vol. 45 ·No. 1 ·2013-01-00 ·Pages 51-8

Guo S, Zhang J, Sun H, Salse J, Lucas WJ, Zhang H, Zheng Y, Mao L, Ren Y, Wang Z, Min J, Guo X, Murat F, Ham BK, Zhang Z, Gao S, Huang M, Xu Y, Zhong S, Bombarely A, Mueller LA, Zhao H, He H, Zhang Y, Zhang Z, Huang S, Tan T, Pang E, Lin K, Hu Q, Kuang H, Ni P, Wang B, Liu J, Kou Q, Hou W, Zou X, Jiang J, Gong G, Klee K, Schoof H, Huang Y, Hu X, Dong S, Liang D, Wang J, Wu K, Xia Y, Zhao X, Zheng Z, Xing M, Liang X, Huang B, Lv T, Wang J, Yin Y, Yi H, Li R, Wu M, Levi A, Zhang X, Giovannoni JJ, Wang J, Li Y, Fei Z, Xu Y

Abstract

Watermelon, Citrullus lanatus, is an important cucurbit crop grown throughout the world. Here we report a high-quality draft genome sequence of the east Asia watermelon cultivar 97103 (2n = 2× = 22) containing 23,440 predicted protein-coding genes. Comparative genomics analysis provided an evolutionary scenario for the origin of the 11 watermelon chromosomes derived from a 7-chromosome paleohexaploid eudicot ancestor. Resequencing of 20 watermelon accessions representing three different C. lanatus subspecies produced numerous haplotypes and identified the extent of genetic diversity and population structure of watermelon germplasm. Genomic regions that were preferentially selected during domestication were identified. Many disease-resistance genes were also found to be lost during domestication. In addition, integrative genomic and transcriptomic analyses yielded important insights into aspects of phloem-based vascular signaling in common between watermelon and cucumber and identified genes crucial to valuable fruit-quality traits, including sugar accumulation and citrulline metabolism.

MeSH Terms
Chromosome Mapping Chromosomes, Plant Citrullus/classification,genetics Computational Biology/methods Evolution, Molecular Gene Expression Profiling Gene Expression Regulation, Plant Genetic Variation Genome, Plant High-Throughput Nucleotide Sequencing Molecular Sequence Annotation Molecular Sequence Data Phylogeny Repetitive Sequences, Nucleic Acid Transcriptome
Authors & Affiliations
66 authors, click to expand affiliations / ORCID
Guo Shaogui
National Engineering Research Center for Vegetables, Beijing Academy of Agriculture and Forestry Sciences, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China), Beijing, China.
Zhang Jianguo
Sun Honghe
Salse Jerome
Lucas William J
Zhang Haiying
Zheng Yi
Mao Linyong
Ren Yi
Wang Zhiwen
Min Jiumeng
Guo Xiaosen
Murat Florent
Ham Byung-Kook
Zhang Zhaoliang
Gao Shan
Huang Mingyun
Xu Yimin
Zhong Silin
Bombarely Aureliano
Mueller Lukas A
Zhao Hong
He Hongju
Zhang Yan
Zhang Zhonghua
Huang Sanwen
Tan Tao
Pang Erli
Lin Kui
Hu Qun
Kuang Hanhui
Ni Peixiang
Wang Bo
Liu Jingan
Kou Qinghe
Hou Wenju
Zou Xiaohua
Jiang Jiao
Gong Guoyi
Klee Kathrin
Schoof Heiko
Huang Ying
Hu Xuesong
Dong Shanshan
Liang Dequan
Wang Juan
Wu Kui
Xia Yang
Zhao Xiang
Zheng Zequn
Xing Miao
Liang Xinming
Huang Bangqing
Lv Tian
Wang Junyi
Yin Ye
Yi Hongping
Li Ruiqiang
Wu Mingzhu
Levi Amnon
Zhang Xingping
Giovannoni James J
Wang Jun
Li Yunfu
Fei Zhangjun
Xu Yong
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Article Info
Journal
Nature genetics
Abbr.
Nat Genet
ISSN
1546-1718
DOI
10.1038/ng.2470
Published
2013-01-00
Epub
2012-00-25
Pages
51-8
Language
English
Region
United States
NLM ID
9216904
Subset
IM
Databases
GENBANK
AGCB00000000, JN402338, JN402339, JX027061, JX027062
Corrections
CommentIn
PMID: 23268131
External Links
PubMed source DOI: 10.1038/ng.2470 View journal details
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