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PMID: 22257949 Published · epublish English Research Support, Non-U.S. Gov't Review

Are snoRNAs and snoRNA host genes new players in cancer?

Nature reviews. Cancer ·Vol. 12 ·No. 2 ·2012-00-19 ·Pages 84-8

Williams GT, Farzaneh F

Abstract

Small nucleolar RNAs (snoRNAs) have long been considered important but unglamorous elements in the production of the protein synthesis machinery of the cell. Recently, however, several independent lines of evidence have indicated that these non-coding RNAs might have crucial roles in controlling cell behaviour, and snoRNA dysfunction could consequently contribute to oncogenesis in previously unsuspected ways.

MeSH Terms
Animals Humans Neoplasms/genetics RNA Processing, Post-Transcriptional RNA, Small Nucleolar/genetics
Chemicals
RNA, Small Nucleolar
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Williams Gwyn T
Institute for Science and Technology in Medicine, Huxley Building, Keele University, Keele ST5 5BG, UK. g.t.williams@keele.ac.uk
Farzaneh Farzin
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Article Info
Journal
Nature reviews. Cancer
Abbr.
Nat Rev Cancer
ISSN
1474-1768
DOI
10.1038/nrc3195
Email
g.t.williams@keele.ac.uk
Published
2012-00-19
Epub
2012-00-19
Pages
84-8
Language
English
Region
England
NLM ID
101124168
Subset
IM
Grants
Biotechnology and Biological Sciences Research Council · BB/E005896/1 · United Kingdom
Department of Health · United Kingdom
External Links
PubMed source DOI: 10.1038/nrc3195 View journal details
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