Home LiteratureArticle Details
PMID: 2173788 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Localization of the receptor gene for type D simian retroviruses on human chromosome 19.

Journal of virology ·Vol. 64 ·No. 12 ·1990-12-00 ·Pages 6214-20

Sommerfelt MA, Williams BP, McKnight A, Goodfellow PN, Weiss RA

Abstract

Simian retrovirus (SRV) serotypes 1 to 5 are exogenous type D viruses causing immune suppression in macaque monkeys. These viruses exhibit receptor interference with each other, with two endogenous type D viruses of the langur (PO-1-Lu) and squirrel monkey, and with two type C retroviruses, feline endogenous virus (RD114/CCC) and baboon endogenous virus (BaEV), indicating that each utilizes the same cell surface receptor (M. A. Sommerfelt and R. A. Weiss, Virology 176:58-69, 1990). Vesicular stomatitis virus pseudotype particles bearing envelope glycoproteins of RD114, BaEV, and the seven SRV strains were employed to detect receptors expressed in human-rodent somatic cell hybrids segregating human chromosomes. The only human chromosome common to all the susceptible hybrids was chromosome 19. By using hybrids retaining different fragments of chromosome 19, a provisional subchromosomal localization of the receptor gene was made to 19q13.1-13.2. Antibodies previously reported to be specific to a BaEV receptor (L. Thiry, J. Cogniaux-Leclerc, R. Olislager, S. Sprecher-Goldberger, and P. Burkens, J. Virol. 48:697-708, 1983) did not block BaEV, RD114, or SRV pseudotypes or syncytia. Antibodies to known surface markers determined by genes mapped to chromosome 19 did not block virus-receptor interaction. The identity of the receptor remains to be determined.

MeSH Terms
Animals Cell Line Cercopithecidae Chromosome Mapping Chromosomes, Human, Pair 19 Cricetinae Humans Hybrid Cells/cytology Macaca Mice Receptors, Virus/genetics,physiology Retroviridae/physiology Saimiri Vesicular stomatitis Indiana virus/genetics
Chemicals
Receptors, Virus
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Sommerfelt M A
Chester Beatty Laboratories, Institute of Cancer Research, London, United Kingdom.
Williams B P
McKnight A
Goodfellow P N
Weiss R A
References (42)
42 references, click to expand
  1. Isolation and propagation of a virus from a spontaneous mammary carcinoma of a rhesus monkey.
    Cancer Res. 1970 Sep;30(9):2388-93 PMID: 4990901
  2. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain.
    Cell. 1986 Nov 7;47(3):333-48 PMID: 3094962
  3. Pseudotypes of vesicular stomatitis virus with the coat of murine leukaemia and of avian myeloblastosis viruses.
    J Gen Virol. 1972 Jun;15(3):183-91 PMID: 4339183
  4. Infectious C-type virus isolated from a baboon placenta.
    Nature. 1974 Mar 1;248(5443):17-20 PMID: 4131937
  5. Responses of infant rhesus monkeys to inoculation with Mason-Pfizer monkey virus materials.
    J Natl Cancer Inst. 1975 Mar;54(3):651-8 PMID: 804565
  6. Interactions between endogenous baboon type-C virus and oncogenic viruses. I. Syncytium induction and development of infectivity assay.
    Int J Cancer. 1975 Nov 15;16(5):747-55 PMID: 171228
  7. Immunological cross reactivity of Mason-Pfizer monkey virus with type C RNA viruses endogenous to primates.
    Nature. 1976 Jun 17;261(5561):609-11 PMID: 180419
  8. Oncornavirus: isolation from a squirrel monkey (Saimiri sciureus) lung culture.
    Science. 1977 Jan 21;195(4275):289-92 PMID: 63993
  9. Identification of mouse chromosomes required for murine leukemia virus replication.
    Cell. 1977 Aug;11(4):949-56 PMID: 196770
  10. A new genetic locus, Bevi, on human chromosome 6 which controls the replication of baboon type C virus in human cells.
    Cell. 1977 Sep;12(1):251-62 PMID: 198140
  11. Isolation and characterization of a new type D retrovirus from the asian primate, Presbytis obscurus (spectacled langur).
    Virology. 1978 Jan;84(1):189-94 PMID: 74122
  12. Primate retroviruses: envelope glycoproteins of endogenous type C and type D viruses possess common interspecies antigenic determinants.
    J Virol. 1978 May;26(2):316-24 PMID: 77909
  13. Assignment of the receptor for ecotropic murine leukemia virus to mouse chromosome 5.
    J Exp Med. 1978 Aug 1;148(2):451-65 PMID: 212501
  14. Type-C and type-D primate retrovirus envelope glycoproteins bind common cellular receptor sites.
    Virology. 1979 Oct 30;98(2):373-84 PMID: 228478
  15. Requirement of human chromosomes 19, 6 and possibly 3 for infection of hamster x human hybrid cells with baboon M7 type C virus.
    Cell. 1979 Sep;18(1):135-43 PMID: 228859
  16. Antibody-mediated neutralization of virus is abrogated by mycoplasma.
    Infect Immun. 1980 Jun;28(3):649-53 PMID: 6249748
  17. Use of vesicular stomatitis virus pseudotypes to map viral receptor genes: Assignment of RD114 virus receptor gene to human chromosome 19.
    J Virol. 1980 Aug;35(2):575-80 PMID: 6255197
  18. Monoclonal antibodies against baboon endogenous virus and against host cell antigens.
    J Virol. 1982 Aug;43(2):664-72 PMID: 6287037
  19. Identification of a cellular receptor for mouse mammary tumor virus and mapping of its gene to chromosome 16.
    J Virol. 1983 Jan;45(1):140-7 PMID: 6296428
  20. Targeted integration of baboon endogenous virus in the BEVI locus on human chromosome 6.
    Nature. 1983 Jan 13;301(5896):129-32 PMID: 6401843
  21. Cell receptors for baboon endogenous virus recognized by monoclonal antibodies.
    J Virol. 1983 Dec;48(3):697-708 PMID: 6415296
  22. Major pol gene progenitors in the evolution of oncoviruses.
    Science. 1984 Jan 27;223(4634):364-70 PMID: 6197754
  23. A new type D retrovirus isolated from macaques with an immunodeficiency syndrome.
    Science. 1984 Feb 10;223(4636):602-5 PMID: 6695172
  24. Characterization of exogenous type D retrovirus from a fibroma of a macaque with simian AIDS and fibromatosis.
    Science. 1984 Apr 20;224(4646):289-2 PMID: 6200929
  25. Isolation of a new serotype of simian acquired immune deficiency syndrome type D retrovirus from Celebes black macaques (Macaca nigra) with immune deficiency and retroperitoneal fibromatosis.
    J Virol. 1985 Nov;56(2):571-8 PMID: 2997477
  26. A cytochrome P-450 gene family mapped to human chromosome 19.
    Ann Hum Genet. 1985 Oct;49(Pt 4):267-74 PMID: 3000277
  27. Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus.
    Cell. 1986 May 9;45(3):375-85 PMID: 2421920
  28. Immunodeficiency in rhesus monkeys associated with the original Mason-Pfizer monkey virus.
    J Natl Cancer Inst. 1986 Oct;77(4):957-65 PMID: 3020302
  29. Sequence relationships of type D retroviruses which cause simian acquired immunodeficiency syndrome.
    Virology. 1987 Apr;157(2):317-29 PMID: 2435057
  30. Regional assignment of five genes on human chromosome 19.
    Chromosoma. 1987;95(1):8-12 PMID: 3034518
  31. The gene for human alpha-lactalbumin is assigned to chromosome 12q13.
    Ann Hum Genet. 1987 Jul;51(Pt 3):183-8 PMID: 3479943
  32. The CD4 antigen: physiological ligand and HIV receptor.
    Cell. 1988 Mar 11;52(5):631-3 PMID: 2830988
  33. The pH independence of mammalian retrovirus infection.
    J Gen Virol. 1990 Apr;71 ( Pt 4):767-73 PMID: 2157795
  34. Receptor interference groups of 20 retroviruses plating on human cells.
    Virology. 1990 May;176(1):58-69 PMID: 1691887
  35. Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus.
    Cell Growth Differ. 1990 Mar;1(3):119-27 PMID: 2078500
  36. Biochemical and genetic analysis of the OKa blood group antigen.
    Immunogenetics. 1988;27(5):322-9 PMID: 3356449
  37. Simian retrovirus D serogroup 1 has a broad cellular tropism for lymphoid and nonlymphoid cells.
    J Virol. 1988 May;62(5):1768-73 PMID: 2965765
  38. Nonhuman primate retrovirus isolates and AIDS.
    Adv Vet Sci Comp Med. 1988;32:171-226 PMID: 2903617
  39. Human T cell leukemia viruses use a receptor determined by human chromosome 17.
    Science. 1988 Dec 16;242(4885):1557-9 PMID: 3201246
  40. Human immunodeficiency virus infection studied in CD4-expressing human-murine T-cell hybrids.
    Virology. 1989 Feb;168(2):267-73 PMID: 2464872
  41. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection.
    Cell. 1989 May 19;57(4):659-66 PMID: 2541919
  42. C-type virus released from cultured human rhabdomyosarcoma cells.
    Nat New Biol. 1972 Jan 5;235(53):3-6 PMID: 4111969
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.64.12.6214-6220.1990
Published
1990-12-00
Pages
6214-20
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC248796
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.64.12.6214-6220.1990 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2