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PMID: 21461660 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Systems biology approaches to abscisic acid signaling.

Journal of plant research ·Vol. 124 ·No. 4 ·2011-07-00 ·Pages 539-48

Umezawa T

Abstract

Recent advances in our understanding of abscisic acid (ABA) signaling have identified a core pathway consisting of receptors (PYR/PYL/RCAR), protein phosphatases (PP2C), protein kinases (SnRK2), and several downstream factors that will lead to the next stage of ABA research. Systems biology will be an important concept for further understanding ABA responses in plants. In this review, two practical approaches of systems biology to ABA signaling are presented: the one is 'transcriptome analysis', which covers coding genes as well as unannotated transcripts, and the other is 'phosphoproteomics'. The latter technology will offer an unprecedented overview of the regulatory networks involved in ABA signaling because protein phosphorylation/dephosphorylation is a major center of such regulation. Systematic studies will contribute to our understanding of the network structure and dynamics of ABA signaling; moreover, systems biology will facilitate ABA signaling studies as well as future biotechnological applications in crops or trees.

MeSH Terms
Abscisic Acid/metabolism GTP-Binding Proteins/metabolism Gene Expression Profiling Gene Expression Regulation, Plant Phosphoprotein Phosphatases/metabolism Phosphorylation Plant Growth Regulators/metabolism Plant Proteins/genetics,metabolism Plant Stomata/physiology Plants/metabolism Protein Serine-Threonine Kinases/metabolism Proteomics Signal Transduction Systems Biology Transcription Factors/metabolism
Chemicals
Plant Growth Regulators Plant Proteins Transcription Factors Abscisic Acid Protein Serine-Threonine Kinases Phosphoprotein Phosphatases GTP-Binding Proteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Umezawa Taishi
Gene Discovery Research Group, RIKEN Plant Science Center, 3-1-1 Kouyadai, Tsukuba, Ibaraki 305-0074, Japan. umezawa@rtc.riken.jp
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Article Info
Journal
Journal of plant research
Abbr.
J Plant Res
ISSN
1618-0860
DOI
10.1007/s10265-011-0418-x
Email
umezawa@rtc.riken.jp
Published
2011-07-00
Epub
2011-00-02
Pages
539-48
Language
English
Region
Japan
NLM ID
9887853
Subset
IM
External Links
PubMed source DOI: 10.1007/s10265-011-0418-x View journal details
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