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PMID: 211086 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Studies on gonococcus infection. XV. Identification of surface proteins of Neisseria gonorrhoeae correlated with leukocyte association.

Infection and immunity ·Vol. 21 ·No. 2 ·1978-08-00 ·Pages 575-84

King GJ, Swanson J

Abstract

Neisseria gonorrhoeae which exhibit high levels of leukocyte association have a surface protein which is considerably diminished in isogenic gonococci which exhibit low levels of leukocyte association (LA). The LA protein exhibits strain variation in molecular weight and immunogenicity. Membranes derived from LA+ and LA- organisms show quantitative differences in their adsorption to leukocytes; these differences are analogous to those found for the intact organisms regarding their association with leukocytes.

MeSH Terms
Animals Bacterial Proteins Cell Membrane/immunology Electrophoresis, Polyacrylamide Gel Gonorrhea/immunology Humans Immune Sera/pharmacology Immunosorbent Techniques Leukocytes/immunology Neisseria gonorrhoeae/immunology Periodic Acid/pharmacology Phagocytosis Rabbits
Chemicals
Bacterial Proteins Immune Sera Periodic Acid
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
King G J
Swanson J
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32 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.21.2.575-584.1978
Published
1978-08-00
Pages
575-84
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC422033
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.21.2.575-584.1978 PMC Full Text View journal details
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