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PMID: 415007 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Studies on gonococcus infection. XIII. Occurrence of color/opacity colonial variants in clinical cultures.

Infection and immunity ·Vol. 19 ·No. 1 ·1978-01-00 ·Pages 332-40

James JF, Swanson J

Abstract

Colonial variants of Neisseria gonorrhoeae differing in color and opacity characteristics are distributed differently between male urethral and female cervical cultures. Colonial characteristics of cultures isolated from female cervices differ with time of isolation within the menstrual cycle and use of oral contraceptives. These differences may reflect selective forces in the ecology of the cervix, particularly proteolytic enzymes in cervical mucus and menstrual blood. Cycle changes in the characteristics of gonococci isolated from females may have implications for pathogenesis of gonococcal infections and immune response to the gonococcus.

MeSH Terms
Cervix Uteri/microbiology Color Contraceptives, Oral/pharmacology Drug Resistance, Microbial Female Genetic Variation Gonorrhea/microbiology Humans Male Menstruation Neisseria gonorrhoeae/drug effects,genetics,growth & development Trypsin/pharmacology Urethra/microbiology
Chemicals
Contraceptives, Oral Trypsin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
James J F
Swanson J
References (22)
22 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1978-01-00
Pages
332-40
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC414084
Subset
IM
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