Home LiteratureArticle Details

PMID: 198746 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Comparison of the nucleotide sequence of the messenger RNA for the major structural protein of SV40 with the DNA sequence encoding the amino acids of the protein.

Nucleic acids research ·Vol. 4 ·No. 8 ·1977-08-00 ·Pages 2549-50

Celma ML, Dhar R, Pan J, Weissman SM

Abstract

The 16S late mRNA from SV40 directs the synthesis of the major viral structural protein, VP1. We have compared the oligonucleotides in the 16S mRNA with those that would be present in a transcript of the portion of SV40 DNA coding for VP1. The results indicate that a segment of about 200 nucleotides of RNA transcribed from a distant part of SV40 DNA have become linked to the transcript of VP1 codons by a bond resistant to phenol extraction and denaturation in formamide.

MeSH Terms

Base Sequence DNA Restriction Enzymes DNA, Viral/metabolism Genes Genetic Code Molecular Weight Oligoribonucleotides/analysis RNA, Messenger/metabolism Ribonuclease T1 Simian virus 40/genetics Viral Proteins/biosynthesis

Chemicals

DNA, Viral Oligoribonucleotides RNA, Messenger Viral Proteins DNA Restriction Enzymes Ribonuclease T1

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Celma M L

Dhar R

Pan J

Weissman S M

References (5)

5 references, click to expand

Nucleotide sequence of simian virus 40 Hind H restriction fragment.
J Mol Biol. 1977 Mar 5;110(3):467-510 PMID: 191620
Structure of a large segment of the genome of simian virus 40 that does not encode known proteins.
Proc Natl Acad Sci U S A. 1977 Mar;74(3):827-31 PMID: 191835
Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli RNA polymerase from a segment of simian virus 40 DNA.
Proc Natl Acad Sci U S A. 1974 Feb;71(2):371-5 PMID: 4360942
Nucleotide sequence about the 3' terminus of SV40 DNA transcripts and the region where DNA synthesis is initiated.
Cold Spring Harb Symp Quant Biol. 1975;39 Pt 1:153-60 PMID: 169054
RNAs of simian virus 40 in productively infected monkey cells: kinetics of formation and decay in enucleate cells.
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2587-91 PMID: 170607

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

Published

1977-08-00

Pages

2549-50

Language

English

Region

England

NLM ID

0411011

PMCID

PMC342591

Subset

Databases

GENBANK

J02400, J02402, J02403, J02406, J02407, J02408, J02409, J02410, V01380

External Links

PubMed source PMC Full Text View journal details

Analysis Services

Comparison of the nucleotide sequence of the messenger RNA for the major structural protein of SV40 with the DNA sequence encoding the amino acids of the protein.

Contact

WeChat Official Account