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PMID: 19871533 Published · ppublish English Journal Article

MOUSE-PROTECTIVE TITERS OF SERA OF VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES.

The Journal of experimental medicine ·Vol. 83 ·No. 4 ·1946-03-31 ·Pages 321-8

Walter AW, Schenkein EL, Sutliff WD

Abstract

1. Sera of human subjects immunized with pneumococci or their type-specific polysaccharides showed type-specific antibody by mouse protection tests as well as on determinations of the specifically precipitable nitrogen. 2. The ratio, mouse-protective units to antibody nitrogen, was less in human sera of low potency than in more potent human or animal sera.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Walter A W
Bureau of Laboratories of the Department of Health of the City of New York, New York.
Schenkein E L
Sutliff W D
References (5)
5 references, click to expand
  1. Immunization against Pneumonia.
    Am J Public Health Nations Health. 1940 Apr;30(4):361-8 PMID: 18015203
  2. ANTIBODY FORMATION IN VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES.
    J Exp Med. 1946 Mar 31;83(4):303-20 PMID: 19871532
  3. SPECIFIC ANTIBODY RESPONSE OF HUMAN SUBJECTS TO INTRACUTANEOUS INJECTION OF PNEUMOCOCCUS PRODUCTS.
    J Exp Med. 1932 May 31;55(6):853-65 PMID: 19870036
  4. CUTANEOUS REACTIONS IN PNEUMONIA. THE DEVELOPMENT OF ANTIBODIES FOLLOWING THE INTRADERMAL INJECTION OF TYPE-SPECIFIC POLYSACCHARIDE.
    J Exp Med. 1930 Sep 30;52(4):573-85 PMID: 19869789
  5. PROPERTIES OF THE TYPE SPECIFIC PROTEINS OF ANTIPNEUMOCOCCUS SERA : I. THE MOUSE PROTECTIVE VALUE OF TYPE I SERA WITH REFERENCE TO THE PRECIPITIN CONTENT.
    J Exp Med. 1937 Sep 30;66(4):413-24 PMID: 19870673
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1946-03-31
Pages
321-8
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2135601
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