IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : I. ESTIMATION OF A AND B ISOANTIBODIES IN HUMAN SERUM BY THE QUANTITATIVE PRECIPITIN METHOD.

The Journal of experimental medicine ·Vol. 82 ·No. 3 ·1945-09-01 ·Pages 207-15

Kabat EA, Bezer AE

Abstract

1. With purified blood group A and B specific substances from the gastric mucin of pigs precipitin reactions can be obtained in sera containing homologous isoagglutinins. By microquantitative precipitin technics the anti-A and anti-B content of normal and immune isoagglutinin-containing sera can be estimated on a weight basis. 2. There was a general correlation between antibody N precipitable from the sera of groups O and B by A substance and the agglutinin titer for A erythrocytes before and after immunization with blood group substances. 3. The reaction between A substance and its homologous isoagglutinin present in the sera of immunized individuals was of the same type as in other antigen-antibody systems.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kabat E A

Department of Neurology, College of Physicians and Surgeons, Columbia University and the Neurological Institute of New York.

Bezer A E

References (8)

8 references, click to expand

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J Exp Med. 1941 Apr 30;73(5):655-67 PMID: 19871103
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Studies in immunochemistry: 7. The isolation from hog gastric mucin of the polysaccharide-amino acid complex possessing blood group A specificity.
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PREPARATION OF THE TYPE-SPECIFIC POLYSACCHARIDE OF THE TYPE I MENINGOCOCCUS AND A STUDY OF ITS EFFECTIVENESS AS AN ANTIGEN IN HUMAN BEINGS.
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THE IMMUNE RESPONSE OF HUMAN BEINGS TO BRIEF INFECTIONS WITH PNEUMOCOCCUS.
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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.82.3.207

Published

1945-09-01

Pages

207-15

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2135546

External Links

PubMed source DOI: 10.1084/jem.82.3.207 PMC Full Text View journal details

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IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : I. ESTIMATION OF A AND B ISOANTIBODIES IN HUMAN SERUM BY THE QUANTITATIVE PRECIPITIN METHOD.

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