The Universal Protein Resource (UniProt) in 2010.
The primary mission of UniProt is to support biological research by maintaining a stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and querying interfaces freely accessible to the scientific community. UniProt is produced by the UniProt Consortium which consists of groups from the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB) and the Protein Information Resource (PIR). UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental Sequence Database. UniProt is updated and distributed every 3 weeks and can be accessed online for searches or download at http://www.uniprot.org.
134 investigators, click to expand
17 references, click to expand
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UniRef: comprehensive and non-redundant UniProt reference clusters.Bioinformatics. 2007 May 15;23(10):1282-8 PMID: 17379688
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UniProt archive.Bioinformatics. 2004 Nov 22;20(17):3236-7 PMID: 15044231
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PIRSF: family classification system at the Protein Information Resource.Nucleic Acids Res. 2004 Jan 1;32(Database issue):D112-4 PMID: 14681371
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The Arabidopsis Information Resource (TAIR): gene structure and function annotation.Nucleic Acids Res. 2008 Jan;36(Database issue):D1009-14 PMID: 17986450
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Gene Ontology annotations at SGD: new data sources and annotation methods.Nucleic Acids Res. 2008 Jan;36(Database issue):D577-81 PMID: 17982175
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Filtering erroneous protein annotation.Bioinformatics. 2004 Aug 4;20 Suppl 1:i342-7 PMID: 15262818
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Infrastructure for the life sciences: design and implementation of the UniProt website.BMC Bioinformatics. 2009 May 08;10:136 PMID: 19426475
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UniProtJAPI: a remote API for accessing UniProt data.Bioinformatics. 2008 May 15;24(10):1321-2 PMID: 18390879
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Ensembl 2008.Nucleic Acids Res. 2008 Jan;36(Database issue):D707-14 PMID: 18000006
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KEGG for linking genomes to life and the environment.Nucleic Acids Res. 2008 Jan;36(Database issue):D480-4 PMID: 18077471
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Collaborative annotation of genes and proteins between UniProtKB/Swiss-Prot and dictyBase.Database (Oxford). 2009;2009:bap016 PMID: 20157489
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A novel method for automatic functional annotation of proteins.Bioinformatics. 1999 Mar;15(3):228-33 PMID: 10222410
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STRING 8--a global view on proteins and their functional interactions in 630 organisms.Nucleic Acids Res. 2009 Jan;37(Database issue):D412-6 PMID: 18940858
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The genome sequence of Schizosaccharomyces pombe.Nature. 2002 Feb 21;415(6874):871-80 PMID: 11859360
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The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes.Genome Res. 2009 Jul;19(7):1316-23 PMID: 19498102
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Petabyte-scale innovations at the European Nucleotide Archive.Nucleic Acids Res. 2009 Jan;37(Database issue):D19-25 PMID: 18978013
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Automated annotation of microbial proteomes in SWISS-PROT.Comput Biol Chem. 2003 Feb;27(1):49-58 PMID: 12798039
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