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PMID: 19414422 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Review

Radioprotection.

In vivo (Athens, Greece) ·Vol. 23 ·No. 2 ·2009-00-00 ·Pages 323-36

Greenberger JS

Abstract

Over 40% of cancer patients will require radiation therapy during management of their disease. Although radiation therapy improves the survival of a significant number of cancer patients, both acute radiation toxicity (which manifests during a course of clinical radiotherapy or shortly thereafter), and late toxicity (developing months to years after completion of radiotherapy) compromise overall outcomes for successfully treated cancer patients.

MeSH Terms
DNA Damage Drug Design Humans Mitochondria/radiation effects Models, Biological Neoplasms/radiotherapy Radiation Injuries/drug therapy,prevention & control Radiation, Ionizing Radiotherapy/adverse effects Radiotherapy Dosage Reactive Oxygen Species Treatment Outcome
Chemicals
Reactive Oxygen Species
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Greenberger Joel S
Department of Radiation Oncology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA. greenbergerjs@upmc.edu
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Article Info
Journal
In vivo (Athens, Greece)
Abbr.
In Vivo
ISSN
0258-851X
Email
greenbergerjs@upmc.edu
Published
2009-00-00
Pages
323-36
Language
English
Region
Greece
NLM ID
8806809
PMCID
PMC2981866
Subset
IM
Grants
NCI NIH HHS · R01 CA083876 · United States
NCI NIH HHS · R01 CA083876-09 · United States
NCI NIH HHS · R01 CA119927 · United States
NIAID NIH HHS · U19AI068021 · United States
External Links
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