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PMID: 19318290 Published · ppublish English Journal Article Review

Inter-kingdom signaling: chemical language between bacteria and host.

Current opinion in microbiology ·Vol. 12 ·No. 2 ·2009-04-00 ·Pages 192-8

Pacheco AR, Sperandio V

Abstract

Chemical communication between cells ensures coordination of behavior. In prokaryotes, this chemical communication is usually referred to as quorum sensing, while eukaryotic cells signal through hormones. In the past years, a growing number of reports have shown that bacterial quorum sensing signals, called autoinducers, signal to eukaryotic cells, mimicking hormones. Conversely, host hormones can signal to bacterial cells through converging pathways to autoinducer signaling. This inter-kingdom signaling mediates symbiotic and pathogenic relationships between bacteria, mammalian and plant hosts.

MeSH Terms
Animals Bacterial Physiological Phenomena Bacterial Proteins Drosophila Proteins Hormones Host-Pathogen Interactions/physiology Humans Mammals/physiology Membrane Proteins Plant Physiological Phenomena Quorum Sensing/physiology Symbiosis/physiology Trans-Activators
Chemicals
Bacterial Proteins Drosophila Proteins Hormones Membrane Proteins Rho protein, Drosophila Trans-Activators
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Pacheco Alline R
Department of Microbiology and Biochemistry, University of Texas Southwestern Medical Center at Dallas, 75390-9048, USA.
Sperandio Vanessa
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Article Info
Journal
Current opinion in microbiology
Abbr.
Curr Opin Microbiol
ISSN
1879-0364
DOI
10.1016/j.mib.2009.01.006
Published
2009-04-00
Epub
2009-00-21
Pages
192-8
Language
English
Region
England
NLM ID
9815056
PMCID
PMC4852728
Subset
IM
Grants
NIAID NIH HHS · R01 AI053067 · United States
NIAID NIH HHS · U01 AI077853 · United States
External Links
PubMed source DOI: 10.1016/j.mib.2009.01.006 PMC Full Text View journal details
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