-
Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling.
EMBO J. 2003 Dec 1;22(23):6277-88
PMID: 14633987
-
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.
Nature. 1998 Jan 29;391(6666):493-6
PMID: 9461217
-
Signal processing by its coil zipper domain activates IKK gamma.
Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1279-84
PMID: 18216269
-
The novel functions of ubiquitination in signaling.
Curr Opin Cell Biol. 2004 Apr;16(2):119-26
PMID: 15196553
-
Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome.
Cell. 1998 Mar 20;92(6):819-28
PMID: 9529257
-
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.
EMBO J. 2008 Jan 23;27(2):373-83
PMID: 18079694
-
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
Mol Cell. 2000 Apr;5(4):649-58
PMID: 10882101
-
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation.
J Biol Chem. 2006 May 12;281(19):13636-13643
PMID: 16543241
-
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses.
Nat Immunol. 2004 Oct;5(10):1052-60
PMID: 15334086
-
Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli.
Science. 2006 Feb 24;311(5764):1141-6
PMID: 16497931
-
Structural basis for recognition of diubiquitins by NEMO.
Mol Cell. 2009 Mar 13;33(5):602-15
PMID: 19185524
-
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
Nat Immunol. 2008 Dec;9(12):1371-8
PMID: 18997794
-
Ubiquitin: a Nobel protein.
Cell. 2004 Dec 17;119(6):741-5
PMID: 15607971
-
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses.
Nat Immunol. 2006 Jun;7(6):606-15
PMID: 16633345
-
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling.
Nat Immunol. 2006 Sep;7(9):962-70
PMID: 16862162
-
In vitro assembly and recognition of Lys-63 polyubiquitin chains.
J Biol Chem. 2001 Jul 27;276(30):27936-43
PMID: 11369780
-
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains.
Mol Cell. 2004 Aug 27;15(4):535-48
PMID: 15327770
-
PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress.
Nat Cell Biol. 2006 Sep;8(9):986-93
PMID: 16906147
-
The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense.
Sci STKE. 2003 Feb 25;2003(171):re3
PMID: 12606705
-
Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair.
Cell. 1999 Mar 5;96(5):645-53
PMID: 10089880
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.
Nature. 2007 Apr 19;446(7138):916-920
PMID: 17392790
-
Two TNF receptors.
Immunol Today. 1992 May;13(5):151-3
PMID: 1322675
-
Productive RUPture: activation of transcription factors by proteasomal processing.
Biochim Biophys Acta. 2004 Nov 29;1695(1-3):209-13
PMID: 15571816
-
Cell biology. Kinasing and clipping down the NF-kappa B trail.
Science. 2005 Apr 1;308(5718):65-6
PMID: 15802594
-
Ubiquitin signalling in the NF-kappaB pathway.
Nat Cell Biol. 2005 Aug;7(8):758-65
PMID: 16056267
-
Mechanisms of ubiquitin-mediated, limited processing of the NF-kappaB1 precursor protein p105.
Biochimie. 2001 Mar-Apr;83(3-4):341-9
PMID: 11295495
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO.
Curr Biol. 2004 Dec 29;14(24):2217-27
PMID: 15620648
-
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide.
Biochem J. 2007 Jun 1;404(2):179-90
PMID: 17348859
-
TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis.
Nat Med. 2006 Sep;12(9):1088-92
PMID: 16921377
-
The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes.
Nat Rev Immunol. 2006 Nov;6(11):799-812
PMID: 17063183
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.
Cell. 2007 Nov 16;131(4):669-81
PMID: 18022362
-
Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology.
Biochem J. 2004 Sep 1;382(Pt 2):393-409
PMID: 15214841
-
Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
J Biol Chem. 2008 Jul 4;283(27):18621-6
PMID: 18467330
-
Two pathways to NF-kappaB.
Mol Cell. 2002 Oct;10(4):693-5
PMID: 12419209
-
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation.
J Virol. 2007 Dec;81(24):13735-42
PMID: 17942533
-
Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation.
Nat Immunol. 2009 Jan;10(1):38-47
PMID: 19060899
-
Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing.
Mol Cell Biol. 2004 Jan;24(1):475-86
PMID: 14673179
-
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis.
EMBO J. 2001 Mar 15;20(6):1271-80
PMID: 11250893
-
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.
Nat Immunol. 2006 Aug;7(8):851-8
PMID: 16799562
-
Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.
Mol Cell Biol. 2008 May;28(10):3538-47
PMID: 18347055
-
A novel type of deubiquitinating enzyme.
J Biol Chem. 2003 Jun 20;278(25):23180-6
PMID: 12682062
-
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein.
Science. 1989 Mar 24;243(4898):1576-83
PMID: 2538923
-
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways.
EMBO Rep. 2005 Apr;6(4):321-6
PMID: 15809659
-
TNF-R1 signaling: a beautiful pathway.
Science. 2002 May 31;296(5573):1634-5
PMID: 12040173
-
Identification of the familial cylindromatosis tumour-suppressor gene.
Nat Genet. 2000 Jun;25(2):160-5
PMID: 10835629
-
Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK.
EMBO Rep. 2007 May;8(5):510-5
PMID: 17363973
-
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death.
J Biol Chem. 2001 Sep 28;276(39):36530-4
PMID: 11479302
-
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.
Nature. 2003 Aug 14;424(6950):801-5
PMID: 12917691
-
NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation.
Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3023-8
PMID: 18287044
-
RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation.
J Biol Chem. 2007 Jun 8;282(23):16776-82
PMID: 17449468
-
A ubiquitin mutant with specific defects in DNA repair and multiubiquitination.
Mol Cell Biol. 1995 Mar;15(3):1265-73
PMID: 7862120
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].
Nat Cell Biol. 2006 Apr;8(4):398-406
PMID: 16547522
-
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell. 2008 Aug 22;134(4):668-78
PMID: 18724939
-
Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.
Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6371-6
PMID: 17404240
-
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.
Oncogene. 1999 Nov 22;18(49):6948-58
PMID: 10602469
-
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.
Mol Cell. 2004 May 7;14(3):289-301
PMID: 15125833
-
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.
Nature. 2004 Jan 8;427(6970):167-71
PMID: 14695475
-
Intracellular NOD-like receptors in host defense and disease.
Immunity. 2007 Oct;27(4):549-59
PMID: 17967410
-
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation.
Cell. 1998 Jun 26;93(7):1231-40
PMID: 9657155
-
Back to the future with ubiquitin.
Cell. 2004 Jan 23;116(2):181-90
PMID: 14744430
-
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.
Nat Genet. 2001 Mar;27(3):277-85
PMID: 11242109
-
Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation.
Blood. 2006 May 15;107(10):4021-9
PMID: 16424386
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway.
Science. 2001 Aug 24;293(5534):1495-9
PMID: 11520989
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO.
Mol Cell. 2006 Apr 21;22(2):245-57
PMID: 16603398
-
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.
Immunity. 1997 Nov;7(5):715-25
PMID: 9390694
-
TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling.
Mol Cell Biol. 2003 Feb;23(4):1231-8
PMID: 12556483
-
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.
J Biol Chem. 2007 Feb 9;282(6):4102-12
PMID: 17135271
-
TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival.
Immunity. 1997 Nov;7(5):703-13
PMID: 9390693
-
NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase.
Mol Cell. 2003 Mar;11(3):685-94
PMID: 12667451
-
TNF-alpha induces two distinct caspase-8 activation pathways.
Cell. 2008 May 16;133(4):693-703
PMID: 18485876
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.
Nature. 2004 Aug 5;430(7000):694-9
PMID: 15258597
-
Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20.
J Mol Biol. 2008 Feb 15;376(2):526-40
PMID: 18164316
-
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.
Nat Cell Biol. 2006 Jul;8(7):700-10
PMID: 16799550
-
Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.
J Biol Chem. 1992 Sep 5;267(25):17971-6
PMID: 1381359
-
DUBA: a deubiquitinase that regulates type I interferon production.
Science. 2007 Dec 7;318(5856):1628-32
PMID: 17991829
-
CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members.
Nature. 2003 Aug 14;424(6950):793-6
PMID: 12917689
-
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif.
EMBO J. 2006 Jul 26;25(14):3257-63
PMID: 16858409
-
Regulation of DNA repair by ubiquitylation.
Nat Rev Mol Cell Biol. 2006 May;7(5):323-34
PMID: 16633336
-
Mechanism and function of deubiquitinating enzymes.
Biochim Biophys Acta. 2004 Nov 29;1695(1-3):189-207
PMID: 15571815
-
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.
EMBO J. 2004 Jan 28;23(2):322-32
PMID: 14713952
-
Expression of the NF-kappaB inhibitor ABIN-3 in response to TNF and toll-like receptor 4 stimulation is itself regulated by NF-kappaB.
J Cell Mol Med. 2008 Jan-Feb;12(1):316-29
PMID: 18081698
-
Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo.
J Immunol. 2008 Jun 1;180(11):7107-11
PMID: 18490708
-
Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling.
J Immunol. 2006 Dec 1;177(11):7520-4
PMID: 17114420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.
Mol Cell. 2001 Feb;7(2):401-9
PMID: 11239468
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK.
Nature. 2001 Jul 19;412(6844):346-51
PMID: 11460167
-
A genomic and functional inventory of deubiquitinating enzymes.
Cell. 2005 Dec 2;123(5):773-86
PMID: 16325574
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes.
Cell. 2003 Jul 25;114(2):181-90
PMID: 12887920
-
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity.
Cell. 1996 Mar 22;84(6):853-62
PMID: 8601309
-
Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling.
Curr Biol. 2007 Mar 6;17(5):418-24
PMID: 17306544
-
Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site.
Nat Struct Mol Biol. 2006 Aug;13(8):691-7
PMID: 16845392
-
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.
Int Immunol. 2006 Oct;18(10):1405-11
PMID: 16940043
-
Ubiquitin: roles in protein modification and breakdown.
Cell. 1983 Aug;34(1):11-2
PMID: 6309404
-
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress.
Cell. 2003 Nov 26;115(5):565-76
PMID: 14651848
-
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20.
Nat Immunol. 2008 Mar;9(3):254-62
PMID: 18246070
-
Essential role of TAK1 in thymocyte development and activation.
Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11677-82
PMID: 16857737
-
Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase.
Mol Cell Biol. 2008 Mar;28(5):1783-91
PMID: 18180283
-
Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.
Cell. 2000 Aug 4;102(3):303-14
PMID: 10975521
-
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.
EMBO J. 2007 Nov 14;26(22):4634-45
PMID: 17948050
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.
Nat Immunol. 2008 Dec;9(12):1364-70
PMID: 18997792
-
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
J Biol Chem. 2004 Jun 18;279(25):26243-50
PMID: 15084608
-
Ubiquitin enters the new millennium.
Mol Cell. 2001 Sep;8(3):499-504
PMID: 11583613
-
Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins.
Oncogene. 2008 Jun 12;27(26):3739-45
PMID: 18212736
-
TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation.
Biochem Biophys Res Commun. 2007 Aug 10;359(4):1044-9
PMID: 17572386
-
The DNA damage response: ten years after.
Mol Cell. 2007 Dec 14;28(5):739-45
PMID: 18082599
-
TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105.
Nature. 1999 Jan 28;397(6717):363-8
PMID: 9950430
-
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.
Cell. 2006 May 19;125(4):665-77
PMID: 16713561
-
Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).
J Biol Chem. 2003 Apr 25;278(17):15429-34
PMID: 12591926
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.
Mol Cell. 2008 Jun 20;30(6):689-700
PMID: 18570872
-
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125.
Proc Natl Acad Sci U S A. 2007 May 1;104(18):7500-5
PMID: 17460044
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice.
Science. 2000 Sep 29;289(5488):2350-4
PMID: 11009421
-
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo.
Dev Cell. 2003 Jun;4(6):799-812
PMID: 12791266
-
p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction.
Genes Dev. 1993 Apr;7(4):705-18
PMID: 8458581
-
Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation.
EMBO J. 2008 Feb 20;27(4):629-41
PMID: 18239685
-
NF-kappaB activation: Nondegradative ubiquitination implicates NEMO.
Trends Immunol. 2006 Sep;27(9):395-7
PMID: 16857427
-
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B.
Cell. 1994 Sep 9;78(5):773-85
PMID: 8087845
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.
Nat Cell Biol. 2009 Feb;11(2):123-32
PMID: 19136968
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.
Nature. 2003 Aug 14;424(6950):797-801
PMID: 12917690
-
TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling.
J Biol Chem. 2008 Nov 28;283(48):33080-6
PMID: 18829460
-
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.
Genes Dev. 1995 Jul 1;9(13):1586-97
PMID: 7628694
-
Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.
Mol Cell Biol. 2005 Dec;25(23):10391-406
PMID: 16287853
-
Structural mechanism of RNA recognition by the RIG-I-like receptors.
Immunity. 2008 Aug 15;29(2):178-81
PMID: 18701081
-
Ubiquitin-binding domains.
Biochem J. 2006 Nov 1;399(3):361-72
PMID: 17034365
-
Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila.
Dev Cell. 2007 Sep;13(3):446-54
PMID: 17765686
-
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module.
Mol Cell. 2008 Feb 29;29(4):451-64
PMID: 18313383
-
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals.
Immunity. 2008 Mar;28(3):381-90
PMID: 18342009
-
Structure of the A20 OTU domain and mechanistic insights into deubiquitination.
Biochem J. 2008 Jan 1;409(1):77-85
PMID: 17961127
-
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity.
Biochem J. 2004 Mar 15;378(Pt 3):727-34
PMID: 14748687
-
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.
J Biol Chem. 2007 Dec 14;282(50):36223-9
PMID: 17947236
-
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer.
Nat Rev Cancer. 2008 Jun;8(6):438-49
PMID: 18500245
-
HTLV-1 Tax-mediated TAK1 activation involves TAB2 adapter protein.
Biochem Biophys Res Commun. 2008 Jan 4;365(1):189-94
PMID: 17986383
-
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.
EMBO Rep. 2008 Sep;9(9):930-6
PMID: 18636086
-
Discovery of HTLV-1, the first human retrovirus, its unique regulatory mechanisms, and insights into pathogenesis.
Oncogene. 2005 Sep 5;24(39):5931-7
PMID: 16155600
-
A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways.
Genes Dev. 1999 Mar 1;13(5):505-10
PMID: 10072378
-
Two distinct ubiquitin-dependent mechanisms are involved in NF-kappaB p105 proteolysis.
Biochem Biophys Res Commun. 2006 Jun 23;345(1):7-13
PMID: 16678126
-
TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL.
PLoS One. 2008;3(12):e4064
PMID: 19112497
-
All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction.
J Cell Sci. 2002 Feb 15;115(Pt 4):679-88
PMID: 11865024
-
Deubiquitylation and regulation of the immune response.
Nat Rev Immunol. 2008 Jul;8(7):501-11
PMID: 18535581
-
Antiviral innate immunity pathways.
Cell Res. 2006 Feb;16(2):141-7
PMID: 16474426
-
Shared principles in NF-kappaB signaling.
Cell. 2008 Feb 8;132(3):344-62
PMID: 18267068
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain.
Cell. 2000 Oct 13;103(2):351-61
PMID: 11057907
-
The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.
J Biol Chem. 2004 Aug 6;279(32):33185-91
PMID: 15175328
-
PIDD mediates NF-kappaB activation in response to DNA damage.
Cell. 2005 Dec 16;123(6):1079-92
PMID: 16360037
-
ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability.
Mol Cell Biol. 2004 Jun;24(12):5235-48
PMID: 15169888