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PMID: 1850185 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Sendai virus NP gene codes for a 524 amino acid NP protein.

Virus genes ·Vol. 5 ·No. 1 ·1991-01-00 ·Pages 25-32

Neubert WJ, Eckerskorn C, Homann HE

Abstract

The complete nucleoprotein (NP) gene sequences of the Sendai virus Fushimi and 6/94 strains were determined. For both viruses an open reading frame of 524 amino acids can be predicted for the NP proteins. By comparing the sequences with others reported in the literature, the 5' noncoding region and the middle third of the coding region were found to be highly conserved. The carboxyl terminal part carries nine amino acid changes and a completely different sequence of the carboxyl terminus with a seven amino acid extension. This carboxyl terminus of the Sendai virus NP protein was confirmed using tryptic peptide sequence analysis.

MeSH Terms
Amino Acid Sequence Base Sequence Cloning, Molecular Codon/genetics Genes, Viral Molecular Sequence Data Nucleoproteins/genetics Open Reading Frames Parainfluenza Virus 1, Human/genetics Peptide Fragments/isolation & purification Protein Conformation RNA, Messenger/genetics Sequence Homology, Nucleic Acid Transcription, Genetic Trypsin
Chemicals
Codon Nucleoproteins Peptide Fragments RNA, Messenger Trypsin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Neubert W J
Abteilung fuer Virusforschung, Max-Planck-Institut fuer Biochemie, Martinsried, FRG.
Eckerskorn C
Homann H E
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Article Info
Journal
Virus genes
Abbr.
Virus Genes
ISSN
0920-8569
DOI
10.1007/BF00571728
Published
1991-01-00
Pages
25-32
Language
English
Region
United States
NLM ID
8803967
Subset
IM
Databases
GENBANK
X17218, X51331
External Links
PubMed source DOI: 10.1007/BF00571728 View journal details
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