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PMID: 17246112 Published · ppublish English Journal Article

Frameshift Suppression in SACCHAROMYCES CEREVISIAE VI. Complete Genetic Map of Twenty-Five Suppressor Genes.

Genetics ·Vol. 103 ·No. 3 ·1983-03-00 ·Pages 389-407

Gaber RF, Mathison L, Edelman I, Culbertson MR

Abstract

Five previously unmapped frameshift suppressor genes have been located on the yeast genetic map. In addition, we have further characterized the map positions of two suppressors whose approximate locations were determined in an earlier study. These results represent the completion of genetic mapping studies on all 25 of the known frameshift suppressor genes in yeast.-The approximate location of each suppressor gene was initially determined through the use of a set of mapping strains containing 61 signal markers distributed throughout the yeast genome. Standard meiotic linkage was assayed in crosses between strains carrying the suppressors and the mapping strains. Subsequent to these approximate linkage determinations, each suppressor gene was more precisely located in multi-point crosses. The implications of these mapping results for the genomic distribution of frameshift suppressor genes, which include both glycine and proline tRNA genes, are discussed.

Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Gaber R F
Laboratory of Molecular Biology, University of Wisconsin, Madison, Wisconsin 53706.
Mathison L
Edelman I
Culbertson M R
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/103.3.389
Published
1983-03-00
Pages
389-407
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1202030
External Links
PubMed source DOI: 10.1093/genetics/103.3.389 PMC Full Text View journal details
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