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PMID: 1658395 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Epstein-Barr virus infection in carcinoma of the salivary gland.

Journal of virology ·Vol. 65 ·No. 12 ·1991-12-00 ·Pages 7032-6

Raab-Traub N, Rajadurai P, Flynn K, Lanier AP

Abstract

Undifferentiated carcinoma of the parotid gland contains clonal Epstein-Barr virus episomes without ladder arrays of restriction enzyme fragments representing virion DNA. Analysis of Epstein-Barr virus transcription in situ in parotid carcinoma specimens revealed that the EBER RNAs, latent membrane protein mRNA, and the BamHI-A rightward reading frame, BARF0, are expressed in the malignant epithelial cells.

MeSH Terms
Alaska Carcinoma/microbiology,pathology DNA, Viral/genetics,isolation & purification Herpesvirus 4, Human/genetics,isolation & purification Humans Inuits Parotid Neoplasms/microbiology,pathology RNA Probes RNA, Viral/genetics,isolation & purification Restriction Mapping Transcription, Genetic Virion/genetics,isolation & purification
Chemicals
DNA, Viral RNA Probes RNA, Viral
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Raab-Traub N
Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599-7295.
Rajadurai P
Flynn K
Lanier A P
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.65.12.7032-7036.1991
Published
1991-12-00
Pages
7032-6
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC250822
Subset
IM
Grants
NCI NIH HHS · CA32979 · United States
External Links
PubMed source DOI: 10.1128/JVI.65.12.7032-7036.1991 PMC Full Text View journal details
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