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PMID: 16453416 Published · ppublish English Journal Article

Nucleotide sequences of yeast genes for tRNA(2), tRNA(2) and tRNA(1): homology blocks occur in the vicinity of different tRNA genes.

The EMBO journal ·Vol. 1 ·No. 3 ·1982-00-00 ·Pages 291-5

Baker RE, Eigel A, Vögtel D, Feldmann H

Abstract

Three members of a collection of pBR322-yeast DNA recombinant plasmids containing yeast tRNA genes have been analyzed and sequenced. Each plasmid carries a single tRNA gene: pY44, tRNA(2); pY41, tRNA(2); pY7, tRNA(1). All three genes are intronless and terminate in a cluster of Ts in the non-coding strand. The sequence information here and previously determined sequences allow an extensive comparison of the regions flanking several yeast tRNA genes. This analysis has revealed novel features in tRNA gene arrangement. Blocks of homology in the flanking regions were found between the tRNA genes of an isoacceptor family but, more interestingly, also between genes coding for tRNAs of different amino-acid specificities. Particularly, three examples are discussed in which sequence elements in the neighborhood of different tRNA genes have been conserved to a high degree and over long distances.

Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Baker R E
Institut für Physiologische Chemie, Physikalische Biochemie und Zellbiologie der Universität, 8000 München 2, Goethestrasse 33, FRG.
Eigel A
Vögtel D
Feldmann H
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1982-00-00
Pages
291-5
Language
English
Region
England
NLM ID
8208664
PMCID
PMC553037
External Links
PubMed source PMC Full Text View journal details
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