Home LiteratureArticle Details
PMID: 16207386 Published · ppublish English Journal Article

Association of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse in Singapore.

Epidemiology and infection ·Vol. 134 ·No. 2 ·2006-04-00 ·Pages 329-32

Sun YJ, Lee AS, Wong SY, Paton NI

Abstract

The relationship of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse was examined. Beijing strains were detected from 32 out of 45 (71%) relapsed cases and 148 out of 290 (51%) non-relapsed cases. Multivariate logistic regression analysis revealed that Beijing genotype was significantly associated with tuberculosis relapse (OR 2.64, 95% CI 1.30-5.34, P=0.005).

MeSH Terms
Adolescent Adult Aged Aged, 80 and over Child Female Genotype Humans Male Middle Aged Mycobacterium tuberculosis/genetics,pathogenicity Odds Ratio Recurrence Singapore/epidemiology Tuberculosis, Pulmonary/genetics,pathology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Sun Y-J
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore. Yong_Jiang_Sun@ttsh.com.sg
Lee A S G
Wong S-Y
Paton N I
References (11)
11 references, click to expand
  1. Mycobacterium tuberculosis Beijing genotype emerging in Vietnam.
    Emerg Infect Dis. 2000 May-Jun;6(3):302-5 PMID: 10827122
  2. High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology.
    Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1901-6 PMID: 11172048
  3. Global dissemination of the Mycobacterium tuberculosis W-Beijing family strains.
    Trends Microbiol. 2002 Jan;10(1):45-52 PMID: 11755085
  4. Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review.
    Emerg Infect Dis. 2002 Aug;8(8):843-9 PMID: 12141971
  5. Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, Vietnam.
    Emerg Infect Dis. 2003 Dec;9(12):1633-5 PMID: 14720411
  6. Recurrent tuberculosis in the United States and Canada: relapse or reinfection?
    Am J Respir Crit Care Med. 2004 Dec 15;170(12):1360-6 PMID: 15477492
  7. Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology.
    J Clin Microbiol. 1993 Feb;31(2):406-9 PMID: 8381814
  8. Predominance of a single genotype of Mycobacterium tuberculosis in countries of east Asia.
    J Clin Microbiol. 1995 Dec;33(12):3234-8 PMID: 8586708
  9. Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology.
    J Clin Microbiol. 1997 Apr;35(4):907-14 PMID: 9157152
  10. Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment.
    N Engl J Med. 1999 Oct 14;341(16):1174-9 PMID: 10519895
  11. Definition of the Beijing/W lineage of Mycobacterium tuberculosis on the basis of genetic markers.
    J Clin Microbiol. 2004 Sep;42(9):4040-9 PMID: 15364987
Article Info
Journal
Epidemiology and infection
Abbr.
Epidemiol Infect
ISSN
0950-2688
Published
2006-04-00
Epub
2005-00-05
Pages
329-32
Language
English
Region
England
NLM ID
8703737
PMCID
PMC2870406
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com