Mycobacterium tuberculosis Beijing genotype emerging in Vietnam.

Emerging infectious diseases ·Vol. 6 ·No. 3 ·2000-00-00 ·Pages 302-5

Anh DD, Borgdorff MW, Van LN, Lan NT, van Gorkom T, Kremer K, van Soolingen D

Abstract

To assess whether the Mycobacterium tuberculosis Beijing genotype is emerging in Vietnam, we analyzed 563 isolates from new cases by spoligotyping and examined the association between the genotype and age, resistance, and BCG vaccination status. Three hundred one (54%) patients were infected with Beijing genotype strains. The genotype was associated with younger age (and hence with active transmission) and with isoniazid and streptomycin resistance, but not with BCG vaccination.

MeSH Terms

Adult Aged Antitubercular Agents/pharmacology BCG Vaccine Drug Resistance, Microbial Female Genotype Humans Male Middle Aged Mycobacterium tuberculosis/classification,drug effects,genetics,isolation & purification Oligodeoxyribonucleotides/genetics Polymerase Chain Reaction Tuberculosis/epidemiology,microbiology Vaccination Vietnam/epidemiology

Chemicals

Antitubercular Agents BCG Vaccine Oligodeoxyribonucleotides

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Anh D D

National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.

Borgdorff M W

Van L N

Lan N T

van Gorkom T

Kremer K

van Soolingen D

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9 references, click to expand

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Article Info

Journal

Emerging infectious diseases

Abbr.

Emerg Infect Dis

ISSN

1080-6040

DOI

10.3201/eid0603.000312

Published

2000-00-00

Pages

302-5

Language

English

Region

United States

NLM ID

9508155

PMCID

PMC2640863

Subset

External Links

PubMed source DOI: 10.3201/eid0603.000312 PMC Full Text View journal details

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