Experimental enteric colibacillosis in piglets.

Eleven of 20 piglets inoculated orally with Escherichia coli:0101:KU460(A):NM and one of 18 piglets inoculated orally with E. coli:08:K87, K88a, b:H19 developed enteric colibacillosis. Successful reproduction of the disease was associated with recovery of a dense growth in a nearly pure culture of the inoculated strain from the feces. Piglets which remained clinically normal had none, or very few, of the inoculated strain in their feces. Seventeen control piglets inoculated orally with the non-enteropathogenic E. coli:043:K -:H28 remained normal.