Studies of Escherichia coli in gnotobiotic pigs 3. Evaluation of orally administered specific antisera.

Canadian journal of comparative medicine and veterinary science ·Vol. 30 ·No. 8 ·1966-08-00 ·Pages 233-7

Kohler EM, Bohl EH

Abstract

The protective effect of orally administered immune (E. COLI 08:K.:H21) serum was demonstrated in experimentally infected gnotobiotic pigs. The temporary protective effect of the immune serum and the correlation of protection with IN VITRO antibody determinations were discussed. The results indicated that the protective action of the immune serum is apparently not dependent upon the complement-antibody bactericidal system. It was suggested that the most plausible mechanism of action of the immune serum was the inactivation of endotoxin in the lumen of the intestine.

MeSH Terms

Animals Diarrhea/complications Escherichia coli/immunology Escherichia coli Infections/immunology Immune Sera/administration & dosage Immunization, Passive Swine Swine Diseases/immunology

Chemicals

Immune Sera

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kohler E M

Bohl E H

References (13)

13 references, click to expand

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Article Info

Journal

Canadian journal of comparative medicine and veterinary science

Abbr.

Can J Comp Med Vet Sci

ISSN

0316-5957

Published

1966-08-00

Pages

233-7

Language

English

Region

Canada

NLM ID

0151757

PMCID

PMC1494563

Subset

External Links

PubMed source PMC Full Text

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Studies of Escherichia coli in gnotobiotic pigs 3. Evaluation of orally administered specific antisera.

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