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PMID: 1568254 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast.

Current genetics ·Vol. 21 ·No. 2 ·1992-02-00 ·Pages 109-16

White MA, Detloff P, Strand M, Petes TD

Abstract

Several investigators have reported that transcription stimulates some types of mitotic recombination in the yeast Saccharomyces cerevisiae. We find that mutations that reduce the rate of transcription of the yeast HIS4 gene in vegetative cells reduce the frequency of mitotic, but not meiotic, recombination events.

Related Genes
HIS4
MeSH Terms
Blotting, Northern Gene Conversion Genes, Fungal Kinetics Meiosis Mitosis Mutation Promoter Regions, Genetic Restriction Mapping Saccharomyces cerevisiae/genetics,physiology Spores, Fungal Transcription, Genetic
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
White M A
Department of Biology, University of North Carolina, Chapel Hill 27599-3218.
Detloff P
Strand M
Petes T D
References (18)
18 references, click to expand
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Article Info
Journal
Current genetics
Abbr.
Curr Genet
ISSN
0172-8083
DOI
10.1007/BF00318468
Published
1992-02-00
Pages
109-16
Language
English
Region
United States
NLM ID
8004904
Subset
IM
Grants
NIGMS NIH HHS · GM24110 · United States
External Links
PubMed source DOI: 10.1007/BF00318468 View journal details
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