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PMID: 1561094 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A protein which specifically binds to single stranded TTAGGGn repeats.

Nucleic acids research ·Vol. 20 ·No. 6 ·1992-03-25 ·Pages 1387-91

McKay SJ, Cooke H

Abstract

Nuclei from tissues of many vertebrates contain a soluble 37 kd protein which binds with a high degree of specificity to oligonucleotides which contain the G rich strand of the telomeric terminal repeats, TTAGGG. In some tissues this is an abundant nuclear protein.

MeSH Terms
Animals Base Sequence DNA, Single-Stranded/metabolism DNA-Binding Proteins/isolation & purification,metabolism Electrophoresis, Polyacrylamide Gel Mice Molecular Sequence Data Repetitive Sequences, Nucleic Acid Species Specificity Telomere/metabolism
Chemicals
DNA, Single-Stranded DNA-Binding Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
McKay S J
Medical Research Council Human Genetics Unit, Western General Hospital, Edinburgh, UK.
Cooke H
References (22)
22 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/20.6.1387
Published
1992-03-25
Pages
1387-91
Language
English
Region
England
NLM ID
0411011
PMCID
PMC312187
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/20.6.1387 PMC Full Text View journal details
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