Abstract
The Comprehensive Yeast Genome Database (CYGD) compiles a comprehensive data resource for information on the cellular functions of the yeast Saccharomyces cerevisiae and related species, chosen as the best understood model organism for eukaryotes. The database serves as a common resource generated by a European consortium, going beyond the provision of sequence information and functional annotations on individual genes and proteins. In addition, it provides information on the physical and functional interactions among proteins as well as other genetic elements. These cellular networks include metabolic and regulatory pathways, signal transduction and transport processes as well as co-regulated gene clusters. As more yeast genomes are published, their annotation becomes greatly facilitated using S.cerevisiae as a reference. CYGD provides a way of exploring related genomes with the aid of the S.cerevisiae genome as a backbone and SIMAP, the Similarity Matrix of Proteins. The comprehensive resource is available under http://mips.gsf.de/genre/proj/yeast/.
MeSH Terms
Binding Sites
Databases, Genetic
Genome, Fungal
Genomics
Membrane Proteins/analysis
Membrane Transport Proteins/analysis,metabolism
Saccharomyces cerevisiae/genetics,metabolism
Saccharomyces cerevisiae Proteins/chemistry,genetics,metabolism
Sequence Analysis, Protein
Transcription Factors/metabolism
User-Computer Interface
Chemicals
Membrane Proteins
Membrane Transport Proteins
Saccharomyces cerevisiae Proteins
Transcription Factors
Authors & Affiliations
20 authors, click to expand affiliations / ORCID
Güldener U
Institute for Bioinformatics, GSF National Research Center for Environment and Health, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany.
Münsterkötter M
Kastenmüller G
Strack N
van Helden J
Lemer C
Richelles J
Wodak S J
García-Martínez J
Pérez-Ortín J E
Michael H
Kaps A
Talla E
Dujon B
André B
Souciet J L
De Montigny J
Bon E
Gaillardin C
Mewes H W
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