The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14.

Genomics ·Vol. 13 ·No. 4 ·1992-08-00 ·Pages 1331-3

Hanson IM, Seawright A, van Heyningen V

Abstract

To map in detail the human gene for brain derived neurotrophic factor (BDNF) we have used a PCR-based assay to amplify the gene from somatic cell hybrids containing human chromosome 11 with deletion or translocation breakpoints in the WAGR region. The BDNF gene maps between the FSHB and HVBS1 loci, an interval of approximately 4 Mb at the boundary of 11p13 and 11p14.

Related Genes

BDNF FSHB HVBS1 WAGR

MeSH Terms

Base Sequence Brain-Derived Neurotrophic Factor Chromosome Deletion Chromosome Mapping Chromosomes, Human, Pair 11 DNA Electrophoresis, Agar Gel Humans Hybrid Cells Molecular Sequence Data Nerve Growth Factors/genetics Nerve Tissue Proteins/genetics Polymerase Chain Reaction

Chemicals

Brain-Derived Neurotrophic Factor Nerve Growth Factors Nerve Tissue Proteins DNA

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Hanson I M

MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom.

Seawright A

van Heyningen V

Article Info

Journal

Genomics

Abbr.

Genomics

ISSN

0888-7543

DOI

10.1016/0888-7543(92)90060-6

Published

1992-08-00

Pages

1331-3

Language

English

Region

United States

NLM ID

8800135

Subset

Grants

Medical Research Council · MC_U127527199 · United Kingdom

External Links

PubMed source DOI: 10.1016/0888-7543(92)90060-6 View journal details

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The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14.

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