Home LiteratureArticle Details
PMID: 14960272 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Early steps in the development of the forebrain.

Developmental cell ·Vol. 6 ·No. 2 ·2004-02-00 ·Pages 167-81

Wilson SW, Houart C

Abstract

The tremendous complexity of the adult forebrain makes it a challenging task to elucidate how this structure forms during embryonic development. Nevertheless, we are beginning to understand how a simple epithelial sheet of ectoderm gives rise to the labyrinthine network of cells that constitutes the functional forebrain. Here, we discuss early events in forebrain development--those that lead to the establishment of the anterior neural plate and the regional subdivision of this territory into the different domains of the prospective forebrain.

MeSH Terms
Animals Body Patterning/genetics,physiology Ectoderm/cytology,physiology Embryonic Induction Gene Expression Regulation, Developmental Homeodomain Proteins/genetics,physiology Morphogenesis/genetics Prosencephalon/cytology,embryology Signal Transduction/physiology Species Specificity Time Factors
Chemicals
Homeodomain Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wilson Stephen W
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom. s.wilson@ucl.ac.uk
Houart Corinne
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Article Info
Journal
Developmental cell
Abbr.
Dev Cell
ISSN
1534-5807
DOI
10.1016/s1534-5807(04)00027-9
Email
s.wilson@ucl.ac.uk
Published
2004-02-00
Pages
167-81
Language
English
Region
United States
NLM ID
101120028
PMCID
PMC2789258
Subset
IM
Grants
Wellcome Trust · 074376 · United Kingdom
External Links
PubMed source DOI: 10.1016/s1534-5807(04)00027-9 PMC Full Text View journal details
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