The occurrence in the rabbit of an acute phase protein analogous to human C reactive protein.
The occurrence in the rabbit of an acute phase protein analogous to human C-reactive protein has been confirmed. The acute phase protein of the rabbit reacts with a special form of the pneumococcal somatic polysaccharide, designated Cx polysaccharide, in the same manner that the human C-reactive protein reacts with the classical C polysaccharide. The method of preparation and some of the properties of the Cx polysaccharide are described. The rabbit Cx-reactive protein has been shown to be remarkably similar to human C-reactive protein in its general properties and in the conditions which govern its appearance in the blood. It has been obtained in crystalline form, and appears to be antigenically distinct from the proteins of normal rabbit serum.
12 references, click to expand
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : I. DISTRIBUTION OF THE REACTIVE PROTEIN IN PATIENTS' SERA AND THE EFFECT OF CALCIUM ON THE FLOCCULATION REACTION WITH C POLYSACCHARIDE OF PNEUMOCOCCUS.J Exp Med. 1941 Jan 31;73(2):173-82 PMID: 19871070
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : IV. CRYSTALLIZATION OF THE C-REACTIVE PROTEIN.J Exp Med. 1947 Apr 30;85(5):491-8 PMID: 19871631
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DECOMPOSITION OF THE CAPSULAR POLYSACCHARIDE OF PNEUMOCOCCUS TYPE III BY A BACTERIAL ENZYME.J Exp Med. 1931 Jun 30;54(1):51-71 PMID: 19869902
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : III. IMMUNOLOGICAL PROPERTIES OF THE C-REACTIVE PROTEIN AND ITS DIFFERENTIATION FROM NORMAL BLOOD PROTEINS.J Exp Med. 1941 Jan 31;73(2):191-200 PMID: 19871072
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AN IMMUNOLOGICAL AND ELECTROPHORETIC COMPARISON OF THE ANTIBODY TO C POLYSACCHARIDE AND THE C-REACTIVE PROTEIN OF ACUTE PHASE SERUM.J Exp Med. 1943 Feb 1;77(2):97-110 PMID: 19871275
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The appearance of acute phase protein after induced fever in man.Acta Med Scand. 1948 Oct 15;131(5):417-21 PMID: 18098991
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CHEMOIMMUNOLOGICAL STUDIES ON THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : I. THE ISOLATION AND PROPERTIES OF THE ACETYL POLYSACCHARIDE OF PNEUMOCOCCUS TYPE I.J Exp Med. 1933 Nov 30;58(6):731-55 PMID: 19870226
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STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : III. AN IMPROVED METHOD FOR THE ISOLATION OF THE TRANSFORMING SUBSTANCE AND ITS APPLICATION TO PNEUMOCOCCUS TYPES II, III, AND VI.J Exp Med. 1946 Jan 31;83(2):97-104 PMID: 19871521
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Determination of C-reactive protein in the blood as a measure of the activity of the disease process in acute rheumatic fever.Am J Med. 1950 Apr;8(4):445-55 PMID: 15410723
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CHEMICAL AND IMMUNOLOGICAL PROPERTIES OF A SPECIES-SPECIFIC CARBOHYDRATE OF PNEUMOCOCCI.J Exp Med. 1930 Nov 30;52(6):895-900 PMID: 19869812
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : II. ISOLATION AND PROPERTIES OF THE REACTIVE PROTEIN.J Exp Med. 1941 Jan 31;73(2):183-90 PMID: 19871071
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SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS.J Exp Med. 1930 Sep 30;52(4):561-71 PMID: 19869788
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