Community-acquired methicillin-resistant Staphylococcus aureus isolated in Switzerland contains the Panton-Valentine leukocidin or exfoliative toxin genes.

Journal of clinical microbiology ·Vol. 42 ·No. 2 ·2004-02-00 ·Pages 825-8

Liassine N, Auckenthaler R, Descombes MC, Bes M, Vandenesch F, Etienne J

Abstract

Among 10 strains of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) isolated in 2002 from patients with skin infections, seven harbored the Panton-Valentine leukocidin gene, two harbored the exfoliative toxin A gene, and one harbored neither of these genes. CA-MRSA isolates producing a variety of exotoxins are currently spreading in the Swiss community.

MeSH Terms

Bacterial Toxins Community-Acquired Infections/transmission Electrophoresis, Gel, Pulsed-Field Exfoliatins/genetics Exotoxins Genes, Bacterial Humans Leukocidins/genetics Methicillin Resistance Skin Diseases, Bacterial/diagnosis,epidemiology Staphylococcal Infections/epidemiology,transmission Staphylococcus aureus/drug effects,genetics,isolation & purification Switzerland/epidemiology

Chemicals

Bacterial Toxins Exfoliatins Exotoxins Leukocidins Panton-Valentine leukocidin

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Liassine Nadia

Bioanalytique-Riotton, Unilabs, 1211 Geneva 2, Switzerland. nlissine@unilabs.ch

Auckenthaler Raymond

Descombes Marie-Christine

Bes Michèle

Vandenesch François

Etienne Jerome

References (16)

16 references, click to expand

egc, a highly prevalent operon of enterotoxin gene, forms a putative nursery of superantigens in Staphylococcus aureus.
J Immunol. 2001 Jan 1;166(1):669-77 PMID: 11123352
Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia.
Clin Infect Dis. 1999 Nov;29(5):1128-32 PMID: 10524952
Epidemiology and clonality of community-acquired methicillin-resistant Staphylococcus aureus in Minnesota, 1996-1998.
Clin Infect Dis. 2001 Oct 1;33(7):990-6 PMID: 11528570
Community-acquired methicillin-resistant Staphylococcus aureus in a rural American Indian community.
JAMA. 2001 Sep 12;286(10):1201-5 PMID: 11559265
Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients.
Lancet. 2002 Mar 2;359(9308):753-9 PMID: 11888586
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan.
J Infect Dis. 2002 May 15;185(10):1511-6 PMID: 11992289
Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2002 Jul;46(7):2155-61 PMID: 12069968
Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin.
Clin Infect Dis. 2002 Oct 1;35(7):819-24 PMID: 12228818
Phenotypic and molecular characterization of community occurring, Western Samoan phage pattern methicillin-resistant Staphylococcus aureus.
J Antimicrob Chemother. 2002 Dec;50(6):825-31 PMID: 12461000
Severity of nonbullous Staphylococcus aureus impetigo in children is associated with strains harboring genetic markers for exfoliative toxin B, Panton-Valentine leukocidin, and the multidrug resistance plasmid pSK41.
J Clin Microbiol. 2003 Jul;41(7):3017-21 PMID: 12843036
Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence.
Emerg Infect Dis. 2003 Aug;9(8):978-84 PMID: 12967497
Identification of methicillin-resistant strains of staphylococci by polymerase chain reaction.
J Clin Microbiol. 1991 Oct;29(10):2240-4 PMID: 1939577
Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk.
JAMA. 1998 Feb 25;279(8):593-8 PMID: 9486753
Community-acquired meticillin-resistant Staphylococcus aureus in Australia. Australian Group on Antimicrobial Resistance.
Lancet. 1998 Jul 11;352(9122):145-6 PMID: 9672301
Community-acquired methicillin-resistant staphylococcus aureus infections.
Pediatr Infect Dis J. 1998 Aug;17(8):745-6 PMID: 9726351
Community-acquired, non-multiresistant oxacillin-resistant Staphylococcus aureus (NORSA) in South Western Sydney.
Pathology. 2001 May;33(2):206-10 PMID: 11358055

Article Info

Journal

Journal of clinical microbiology

Abbr.

J Clin Microbiol

ISSN

0095-1137

DOI

10.1128/JCM.42.2.825-828.2004

nlissine@unilabs.ch

Published

2004-02-00

Pages

825-8

Language

English

Region

United States

NLM ID

7505564

PMCID

PMC344453

Subset

External Links

PubMed source DOI: 10.1128/JCM.42.2.825-828.2004 PMC Full Text View journal details

Analysis Services

Community-acquired methicillin-resistant Staphylococcus aureus isolated in Switzerland contains the Panton-Valentine leukocidin or exfoliative toxin genes.

Contact

WeChat Official Account