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PMID: 14293010 Published · ppublish English Journal Article

PHENETHYL ALCOHOL. II. EFFECT ON THYMINE-REQUIRING ESCHERICHIA COLI.

Journal of bacteriology ·Vol. 89 ·1965-05-00 ·Pages 1370-3

ROSENKRANZ HS, CARR HS, ROSE HM

Abstract

Rosenkranz, Herbert S. (Columbia University, New York, N.Y.), Howard S. Carr, and Harry M. Rose. Phenethyl alcohol. II. Effect on thymine-requiring Escherichia coli. J. Bacteriol. 89:1370-1373. 1965.-Phenethyl alcohol (PEA) at levels (0.05%) presumed to interfere with messenger ribonucleic acid synthesis also inhibits thymineless death, when the agent is added prior to the exponential killing phase. The addition of more concentrated solutions of PEA (0.5%) during this initial starvation leads to an immediate killing. Identical results were obtained when 0.5% PEA was added to cells growing in the presence of thymine. The addition of this high level (0.5%) of PEA to bacteria undergoing thymineless death results in the rescue of the survivors.

Keywords
ALCOHOLS COLIPHAGES ESCHERICHIA COLI EXPERIMENTAL LAB STUDY METABOLISM PHARMACOLOGY RNA MESSENGER THYMINE
MeSH Terms
Alcohols Coliphages Escherichia coli Metabolism Pharmacology Phenylethyl Alcohol RNA RNA, Bacterial RNA, Messenger Research Thymine
Chemicals
Alcohols RNA, Bacterial RNA, Messenger RNA Phenylethyl Alcohol Thymine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
ROSENKRANZ H S
CARR H S
ROSE H M
References (20)
20 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1965-05-00
Pages
1370-3
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC277653
Subset
OM
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