The relationship between the acute phase response and antibody production in the rabbit. I. Correlation between the early appearance of Cx-reaction protein and subsequent antibody production.

The Journal of experimental medicine ·Vol. 98 ·No. 4 ·1953-10-00 ·Pages 311-9

WOOD HF

Abstract

It has been found that some rabbits respond to the administration of either human C-reactive protein or human gamma globulin with the production of an acute phase substance, Cx-reactive protein. A correlation was found to exist between the amount of Cx-protein produced and the subsequent production of significant titers of precipitating antibody to the two antigens employed.

Keywords

ANTIGENS AND ANTIBODIES PROTEINS

MeSH Terms

Acute-Phase Reaction Animals Antibodies Antibody Formation Antigens C-Reactive Protein Humans Proteins Rabbits

Chemicals

Antibodies Antigens Proteins C-Reactive Protein

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

WOOD H F

References (7)

7 references, click to expand

Effect of cortisone on experimental acute disseminated encephalomyelitis.
Trans Am Neurol Assoc. 1951;56:128-30 PMID: 14913604
The measurement of C-reactive protein in human sera; comparison of the clinical tests on the basis of a quantitative method.
J Clin Invest. 1951 Jun;30(6):616-22 PMID: 14841262
Effect of cortisone on experimental fractures in the rabbit.
Proc Soc Exp Biol Med. 1950 Apr;73(4):678-81 PMID: 15417638
Determination of C-reactive protein in the blood as a measure of the activity of the disease process in acute rheumatic fever.
Am J Med. 1950 Apr;8(4):445-55 PMID: 15410723
Relation between certain myeloma proteins and normal gamma globulin.
Proc Soc Exp Biol Med. 1951 Jan;76(1):190-3 PMID: 14816435
The occurrence in the rabbit of an acute phase protein analogous to human C reactive protein.
J Exp Med. 1951 Jan;93(1):25-36 PMID: 14803629
TYPING GROUP A HEMOLYTIC STREPTOCOCCI BY M PRECIPITIN REACTIONS IN CAPILLARY PIPETTES.
J Exp Med. 1943 Aug 1;78(2):127-33 PMID: 19871314

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.98.4.311

Published

1953-10-00

Pages

311-9

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2136250

Subset

External Links

PubMed source DOI: 10.1084/jem.98.4.311 PMC Full Text View journal details

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The relationship between the acute phase response and antibody production in the rabbit. I. Correlation between the early appearance of Cx-reaction protein and subsequent antibody production.

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