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PMID: 12880177 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Parallel fiber receptive fields: a key to understanding cerebellar operation and learning.

Cerebellum (London, England) ·Vol. 2 ·No. 2 ·2003-00-00 ·Pages 101-9

Ekerot CF, Jörntell H

Abstract

In several theories of the function of the cerebellum in motor control, the mossy-fiber-parallel fiber input has been suggested to provide information used in the control of ongoing movements whereas the role of climbing fibers is to induce plastic changes of parallel fiber (PF) synapses on Purkinje cells. From studies of climbing fibers during the last few decades, we have gained detailed knowledge about the zonal and microzonal organization of the cerebellar cortex and the information carried by climbing fibers. However, properties of the PF input to Purkinje cells and inhibitory interneurones have been largely unknown. The present review, which focuses on the C3 zone of the cerebellar anterior lobe, will present and discuss recent data of the cutaneous PF input to Purkinje cells, interneurons and Golgi cells as well as novel forms of PF plasticity.

MeSH Terms
Animals Cerebellum/physiology Humans Interneurons/physiology Learning/physiology Long-Term Potentiation Models, Neurological Nerve Fibers/physiology Purkinje Cells/physiology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ekerot Carl-Fredrik
Department of Physiological Sciences, Section for Neurophysiology, Lund University, Sweden. carl-fredrik.ekerot@mphy.lu.se
Jörntell Henrik
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Article Info
Journal
Cerebellum (London, England)
Abbr.
Cerebellum
ISSN
1473-4222
DOI
10.1080/14734220309411
Email
carl-fredrik.ekerot@mphy.lu.se
Published
2003-00-00
Pages
101-9
Language
English
Region
United States
NLM ID
101089443
Subset
IM
External Links
PubMed source DOI: 10.1080/14734220309411 View journal details
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