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PMID: 12537571 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Apollo: a sequence annotation editor.

Genome biology ·Vol. 3 ·No. 12 ·2002-00-00 ·Pages RESEARCH0082

Lewis SE, Searle SM, Harris N, Gibson M, Lyer V, Richter J, Wiel C, Bayraktaroglu L, Birney E, Crosby MA, Kaminker JS, Matthews BB, Prochnik SE, Smithy CD, Tupy JL, Rubin GM, Misra S, Mungall CJ, Clamp ME

Abstract

The well-established inaccuracy of purely computational methods for annotating genome sequences necessitates an interactive tool to allow biological experts to refine these approximations by viewing and independently evaluating the data supporting each annotation. Apollo was developed to meet this need, enabling curators to inspect genome annotations closely and edit them. FlyBase biologists successfully used Apollo to annotate the Drosophila melanogaster genome and it is increasingly being used as a starting point for the development of customized annotation editing tools for other genome projects.

MeSH Terms
Animals Database Management Systems Databases, Nucleic Acid Humans Software Design User-Computer Interface
Authors & Affiliations
19 authors, click to expand affiliations / ORCID
Lewis S E
Department of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA 94720-3200, USA. suzi@fruitfly.org
Searle S M J
Harris N
Gibson M
Lyer V
Richter J
Wiel C
Bayraktaroglu L
Birney E
Crosby M A
Kaminker J S
Matthews B B
Prochnik S E
Smithy C D
Tupy J L
Rubin G M
Misra S
Mungall C J
Clamp M E
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Article Info
Journal
Genome biology
Abbr.
Genome Biol
ISSN
1474-760X
DOI
10.1186/gb-2002-3-12-research0082
Email
suzi@fruitfly.org
Published
2002-00-00
Epub
2002-00-23
Pages
RESEARCH0082
Language
English
Region
England
NLM ID
100960660
PMCID
PMC151184
Subset
IM
Grants
NHGRI NIH HHS · P41 HG000739 · United States
NHGRI NIH HHS · U41 HG000739 · United States
NHGRI NIH HHS · HG00739 · United States
NHGRI NIH HHS · HG00750 · United States
External Links
PubMed source DOI: 10.1186/gb-2002-3-12-research0082 PMC Full Text View journal details
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