Lysozymuria in diabetes.

British medical journal ·Vol. 1 ·No. 6010 ·1976-03-13 ·Pages 624-5

Farr M, Wardle EN, Wilkinson K

Abstract

A reversible lysozymuria indicative of proximal tubular damage to the kidney was found in three out of five patients with diabetic ketosis, and a persistent lysozymuria was found in many patients with diabetic nephropathy. There was no relation between lysozymuria and the degree of proteinuria, and lysozymuria was not due to urinary tract infection. The degree of lysozymuria could be used to assess the severity of diabetic nephropathy.

MeSH Terms

Creatinine/urine Diabetic Nephropathies/enzymology,urine Glomerulonephritis/enzymology,urine Multiple Myeloma/enzymology Muramidase/urine Proteinuria/urine Pyelonephritis/enzymology,urine

Chemicals

Creatinine Muramidase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Farr M

Wardle E N

Wilkinson K

References (7)

7 references, click to expand

Clinical diagnostic value of lysozymuria.
Adv Nephrol Necker Hosp. 1971;1:195-205 PMID: 5006256
Urinary muramidase and renal disease. Correlation with renal histology and implication for the mechanism of enzymuria.
N Engl J Med. 1968 Sep 5;279(10):506-12 PMID: 5671455
Simple method for detection of infection of peritoneum during dialysis.
Br Med J. 1973 Jun 2;2(5865):518-20 PMID: 4541368
The natural history of diabetic renal disease. A follow-up study of a series of renal biopsies.
Q J Med. 1972 Oct;41(164):437-56 PMID: 4564622
Lysozymuria and acute disorders of renal function.
J Clin Pathol. 1973 Apr;26(4):278-84 PMID: 4701797
Selective changes in white cell lysosomal enzymes in man.
Am J Med Sci. 1968 May;255:327-35 PMID: 5239750
Lysozyme excretion as a measure of renal tubular dysfunction in children.
Clin Sci. 1970 Sep;39(3):457-65 PMID: 5459170

Article Info

Journal

British medical journal

Abbr.

Br Med J

ISSN

0007-1447

DOI

10.1136/bmj.1.6010.624

Published

1976-03-13

Pages

624-5

Language

English

Region

England

NLM ID

0372673

PMCID

PMC1639011

Subset

External Links

PubMed source DOI: 10.1136/bmj.1.6010.624 PMC Full Text

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Lysozymuria in diabetes.

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