Simple method for detection of infection of peritoneum during dialysis.

British medical journal ·Vol. 2 ·No. 5865 ·1973-06-02 ·Pages 518-20

Wardle EN

Abstract

The lysozyme (muramidase) content of peritoneal fluid samples has been found to be an early indicator of the onset of infection in the course of peritoneal dialysis. A level of 10.0 mug/ml indicates peritoneal infection and one of 7.5 mug/ml is highly suspicious.

MeSH Terms

Ascitic Fluid/enzymology Gastrointestinal Hemorrhage/enzymology Heparin/pharmacology,therapeutic use Humans Kanamycin/therapeutic use Muramidase/antagonists & inhibitors,blood,metabolism Pancreatitis/enzymology Peritoneal Dialysis Peritonitis/diagnosis,drug therapy,enzymology

Chemicals

Kanamycin Heparin Muramidase

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Wardle E N

References (9)

9 references, click to expand

Further Experiences with Peritoneal Irrigation for Acute Renal Failure: Including a Description of Modifications in Method.
Ann Surg. 1948 Sep;128(3):561-608 PMID: 17859220
Urinary lysozyme, ribonuclease, and low-molecular-weight protein in renal disease.
Lancet. 1968 Feb 24;1(7539):371-5 PMID: 4169970
Plasma beta-lysin and lysozyme following endotoxin administration and the generalized Shwartzman reaction.
Proc Soc Exp Biol Med. 1971 Feb;136(2):473-8 PMID: 5544480
Lysozyme turnover in man.
J Clin Invest. 1972 May;51(5):1146-55 PMID: 4502451
A STUDY OF URINARY AND SERUM LYSOZYME IN PATIENTS WITH RENAL DISEASE.
N Engl J Med. 1964 Feb 6;270:269-74 PMID: 14074651
Selective changes in white cell lysosomal enzymes in man.
Am J Med Sci. 1968 May;255:327-35 PMID: 5239750
Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia.
J Exp Med. 1966 Nov 1;124(5):921-52 PMID: 5224561
Peritoneal and haemodialysis: a comparison of their morbidity, and of the mortality suffered by dialysed patients.
Q J Med. 1966 Jul;35(139):407-20 PMID: 5957643
Simplified peritoneal dialysis.
Lancet. 1970 Feb 7;1(7641):297 PMID: 4189308

Article Info

Journal

British medical journal

Abbr.

Br Med J

ISSN

0007-1447

DOI

10.1136/bmj.2.5865.518

Published

1973-06-02

Pages

518-20

Language

English

Region

England

NLM ID

0372673

PMCID

PMC1589559

Subset

External Links

PubMed source DOI: 10.1136/bmj.2.5865.518 PMC Full Text

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Simple method for detection of infection of peritoneum during dialysis.

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