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PMID: 12520006 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

GPCRDB information system for G protein-coupled receptors.

Nucleic acids research ·Vol. 31 ·No. 1 ·2003-01-01 ·Pages 294-7

Horn F, Bettler E, Oliveira L, Campagne F, Cohen FE, Vriend G

Abstract

The GPCRDB is a molecular class-specific information system that collects, combines, validates and disseminates heterogeneous data on G protein-coupled receptors (GPCRs). The database stores data on sequences, ligand binding constants and mutations. The system also provides computationally derived data such as sequence alignments, homology models, and a series of query and visualization tools. The GPCRDB is updated automatically once every 4-5 months and is freely accessible at http://www.gpcr.org/7tm/.

MeSH Terms
Amino Acid Sequence Computational Biology Databases, Protein Heterotrimeric GTP-Binding Proteins/metabolism Humans Information Systems Ligands Models, Molecular Mutation Receptors, Cell Surface/chemistry,genetics,metabolism Sequence Alignment
Chemicals
Ligands Receptors, Cell Surface Heterotrimeric GTP-Binding Proteins
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Horn Florence
Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA.
Bettler Emmanuel
Oliveira Laerte
Campagne Fabien
Cohen Fred E
Vriend Gerrit
References (12)
12 references, click to expand
  1. Visualisation and integration of G protein-coupled receptor related information help the modelling: description and applications of the Viseur program.
    J Comput Aided Mol Des. 1999 Nov;13(6):625-43 PMID: 10584220
  2. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.
    Nucleic Acids Res. 2000 Jan 1;28(1):45-8 PMID: 10592178
  3. TinyGRAP database: a bioinformatics tool to mine G-protein-coupled receptor mutant data.
    Trends Pharmacol Sci. 1999 Dec;20(12):475-7 PMID: 10603488
  4. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
    Nat Genet. 2000 May;25(1):25-9 PMID: 10802651
  5. Interactive construction of residue-based diagrams of proteins: the RbDe web service.
    Protein Eng. 2000 Jun;13(6):395-6 PMID: 10877849
  6. The interaction of class B G protein-coupled receptors with their hormones.
    Receptors Channels. 1998;5(5):305-14 PMID: 9666522
  7. Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems.
    Nucleic Acids Res. 2001 Jan 1;29(1):346-9 PMID: 11125133
  8. The EMBL Nucleotide Sequence Database.
    Nucleic Acids Res. 2002 Jan 1;30(1):21-6 PMID: 11752244
  9. G-protein-coupled receptor websites.
    Trends Pharmacol Sci. 2002 Nov;23(11):535-6 PMID: 12413809
  10. WHAT IF: a molecular modeling and drug design program.
    J Mol Graph. 1990 Mar;8(1):52-6, 29 PMID: 2268628
  11. Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function.
    J Mol Med (Berl). 1995 Feb;73(2):51-63 PMID: 7627630
  12. Crystal structure of rhodopsin: A G protein-coupled receptor.
    Science. 2000 Aug 4;289(5480):739-45 PMID: 10926528
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkg103
Published
2003-01-01
Pages
294-7
Language
English
Region
England
NLM ID
0411011
PMCID
PMC165550
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/gkg103 PMC Full Text View journal details
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