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PMID: 12391011 Published · ppublish English Journal Article Comment

A plague on host defense.

The Journal of experimental medicine ·Vol. 196 ·No. 8 ·2002-10-21 ·Pages 1009-12

Kopp E, Medzhitov R

Abstract

暂无摘要

MeSH Terms
Antigens, Bacterial/immunology Bacterial Proteins/physiology Virulence Yersinia pestis/immunology,pathogenicity,physiology
Chemicals
Antigens, Bacterial Bacterial Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kopp Elizabeth
Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
Medzhitov Ruslan
References (27)
27 references, click to expand
  1. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.
    Nature. 1999 Oct 21;401(6755):811-5 PMID: 10548109
  2. Virulence role of V antigen of Yersinia pestis at the bacterial surface.
    Infect Immun. 1999 Oct;67(10):5395-408 PMID: 10496922
  3. Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway.
    J Immunol. 2000 Jan 15;164(2):554-7 PMID: 10623793
  4. Molecular and cell biology aspects of plague.
    Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8778-83 PMID: 10922034
  5. LcrV, a substrate for Yersinia enterocolitica type III secretion, is required for toxin targeting into the cytosol of HeLa cells.
    J Biol Chem. 2000 Nov 24;275(47):36869-75 PMID: 10930402
  6. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
    Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13766-71 PMID: 11095740
  7. Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways.
    J Immunol. 2000 Dec 15;165(12):7096-101 PMID: 11120839
  8. A Toll-like receptor recognizes bacterial DNA.
    Nature. 2000 Dec 7;408(6813):740-5 PMID: 11130078
  9. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.
    Nature. 2001 Apr 26;410(6832):1099-103 PMID: 11323673
  10. Common and contrasting themes of plant and animal diseases.
    Science. 2001 Jun 22;292(5525):2285-9 PMID: 11423652
  11. Discrimination of bacterial lipoproteins by Toll-like receptor 6.
    Int Immunol. 2001 Jul;13(7):933-40 PMID: 11431423
  12. Toll-like receptors: critical proteins linking innate and acquired immunity.
    Nat Immunol. 2001 Aug;2(8):675-80 PMID: 11477402
  13. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
    Nature. 2001 Oct 18;413(6857):732-8 PMID: 11607032
  14. Yersinia enterocolitica evasion of the host innate immune response by V antigen-induced IL-10 production of macrophages is abrogated in IL-10-deficient mice.
    J Immunol. 2002 Feb 1;168(3):1315-21 PMID: 11801671
  15. Toll-like receptors and innate immunity.
    Nat Rev Immunol. 2001 Nov;1(2):135-45 PMID: 11905821
  16. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.
    J Immunol. 2002 Jul 1;169(1):10-4 PMID: 12077222
  17. A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways.
    Int Immunol. 2002 Jul;14(7):783-91 PMID: 12096038
  18. Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice.
    Nat Med. 2002 Aug;8(8):878-84 PMID: 12091878
  19. Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression.
    J Exp Med. 2002 Oct 21;196(8):1017-24 PMID: 12391013
  20. Approaching the asymptote? Evolution and revolution in immunology.
    Cold Spring Harb Symp Quant Biol. 1989;54 Pt 1:1-13 PMID: 2700931
  21. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
    Immunity. 1999 Oct;11(4):443-51 PMID: 10549626
  22. The virulence plasmid of Yersinia, an antihost genome.
    Microbiol Mol Biol Rev. 1998 Dec;62(4):1315-52 PMID: 9841674
  23. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.
    Science. 1998 Dec 11;282(5396):2085-8 PMID: 9851930
  24. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
    J Exp Med. 1999 Feb 15;189(4):615-25 PMID: 9989976
  25. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.
    J Immunol. 1999 Apr 1;162(7):3749-52 PMID: 10201887
  26. Type III secretion machines: bacterial devices for protein delivery into host cells.
    Science. 1999 May 21;284(5418):1322-8 PMID: 10334981
  27. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2.
    J Biol Chem. 1999 Jun 18;274(25):17406-9 PMID: 10364168
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
2002-10-21
Pages
1009-12
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2194040
Subset
IM
Corrections
CommentOn
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