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Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue.
Brain Res Mol Brain Res. 1999 May 21;69(1):93-103
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Signaling routes to CREM and CREB: plasticity in transcriptional activation.
Trends Biochem Sci. 1999 Jul;24(7):281-5
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The role of position a in determining the stability and oligomerization state of alpha-helical coiled coils: 20 amino acid stability coefficients in the hydrophobic core of proteins.
Protein Sci. 1999 Nov;8(11):2312-29
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Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins.
Mol Cell Biol. 2000 Feb;20(3):912-8
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J Biol Chem. 2000 Sep 1;275(35):27013-20
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Structural basis for the diversity of DNA recognition by bZIP transcription factors.
Nat Struct Biol. 2000 Oct;7(10):889-93
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Interhelical ion pairing in coiled coils: solution structure of a heterodimeric leucine zipper and determination of pKa values of Glu side chains.
Biochemistry. 2000 Oct 24;39(42):12804-18
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Attractive interhelical electrostatic interactions in the proline- and acidic-rich region (PAR) leucine zipper subfamily preclude heterodimerization with other basic leucine zipper subfamilies.
J Biol Chem. 2000 Nov 3;275(44):34826-32
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The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding.
J Biol Chem. 2000 Nov 10;275(45):35242-7
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DNA sequence-dependent folding determines the divergence in binding specificities between Maf and other bZIP proteins.
EMBO J. 2001 Feb 15;20(4):828-40
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The sequence of the human genome.
Science. 2001 Feb 16;291(5507):1304-51
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Nature. 2001 Feb 15;409(6822):832-3
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Nature. 2001 Feb 15;409(6822):860-921
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CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression.
Nucleic Acids Res. 2001 May 15;29(10):2154-62
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Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation.
J Biol Chem. 2001 Jun 15;276(24):20858-65
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Oncogene. 2001 Apr 30;20(19):2390-400
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Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity.
Oncogene. 2001 Apr 30;20(19):2438-52
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Gene. 2001 Jul 25;273(1):1-11
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Nat Rev Mol Cell Biol. 2001 Aug;2(8):599-609
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Nature. 1987 Jul 9-15;328(6126):175-8
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Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.
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Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.
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Cell. 1988 Feb 12;52(3):415-23
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Science. 1988 Jun 24;240(4860):1759-64
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The role of the leucine zipper in the fos-jun interaction.
Nature. 1988 Dec 15;336(6200):646-51
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Science. 1988 Dec 9;242(4884):1430-3
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Isolation of a recombinant copy of the gene encoding C/EBP.
Genes Dev. 1988 Jul;2(7):786-800
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In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage.
Genes Dev. 1988 Jul;2(7):801-6
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Proc Natl Acad Sci U S A. 1989 Mar;86(5):1500-3
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Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper.
Science. 1995 Apr 21;268(5209):436-9
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Transcriptional activation by DNA-binding derivatives of HSV-1 VP16 that lack the carboxyl-terminal acidic activation domain.
Virology. 1995 May 10;209(1):19-28
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Extending dimerization interfaces: the bZIP basic region can form a coiled coil.
EMBO J. 1995 Nov 1;14(21):5329-37
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Design of a C/EBP-specific, dominant-negative bZIP protein with both inhibitory and gain-of-function properties.
J Biol Chem. 1996 Jan 26;271(4):2040-7
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The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core.
Nucleic Acids Res. 1996 May 15;24(10):1855-64
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The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite.
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Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.
Science. 1989 Mar 31;243(4899):1689-94
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Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains.
Science. 1989 Mar 31;243(4899):1695-9
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Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.
Genes Dev. 1989 Jun;3(6):770-81
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Scissors-grip model for DNA recognition by a family of leucine zipper proteins.
Science. 1989 Nov 17;246(4932):911-6
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The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.
EMBO J. 1989 Dec 20;8(13):4229-38
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Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.
Genes Dev. 1989 Dec;3(12B):2083-90
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Different requirements for formation of Jun: Jun and Jun: Fos complexes.
Genes Dev. 1989 Dec;3(12B):2091-100
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Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1.
Oncogene. 1990 Apr;5(4):451-8
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Alpha-helical coiled coils and bundles: how to design an alpha-helical protein.
Proteins. 1990;7(1):1-15
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Analysis of dimerization and DNA binding functions in Fos and Jun by domain-swapping: involvement of residues outside the leucine zipper/basic region.
Oncogene. 1990 Jun;5(6):929-39
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Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.
EMBO J. 1990 Aug;9(8):2537-42
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Evidence of changes in protease sensitivity and subunit exchange rate on DNA binding by C/EBP.
Science. 1990 Aug 17;249(4970):771-4
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Design of DNA-binding peptides based on the leucine zipper motif.
Science. 1990 Aug 17;249(4970):774-8
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Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles.
Biochemistry. 1990 Oct 9;29(40):9343-52
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Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex.
Nucleic Acids Res. 1990 Dec 11;18(23):6871-80
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Strength and co-operativity of contributions of surface salt bridges to protein stability.
J Mol Biol. 1990 Dec 20;216(4):1031-44
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A single site mutation in a truncated Fos protein allows it to interact with the TRE in vitro.
Oncogene. 1991 Jan;6(1):173-9
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Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.
Proc Natl Acad Sci U S A. 1991 May 1;88(9):3720-4
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c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.
Oncogene. 1991 Apr;6(4):533-42
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Identification of multiple nuclear factors that interact with cyclic adenosine 3',5'-monophosphate response element-binding protein and activating transcription factor-2 by protein-protein interactions.
Mol Endocrinol. 1991 Feb;5(2):256-66
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Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.
Genes Dev. 1991 Sep;5(9):1538-52
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A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.
Genes Dev. 1991 Sep;5(9):1553-67
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Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis.
Mech Dev. 1991 Mar;34(1):3-9
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TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.
Genes Dev. 1991 Oct;5(10):1739-53
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Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP.
Mol Cell Biol. 1991 Oct;11(10):4863-75
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X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.
Science. 1991 Oct 25;254(5031):539-44
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Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization.
Trends Biochem Sci. 1991 Nov;16(11):417-22
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Mechanism of specificity in the Fos-Jun oncoprotein heterodimer.
Cell. 1992 Feb 21;68(4):699-708
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Structure of the leucine zipper.
Curr Opin Genet Dev. 1992 Apr;2(2):205-10
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Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.
Genes Dev. 1992 Sep;6(9):1608-20
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The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex.
Cell. 1992 Dec 24;71(7):1223-37
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Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1.
J Biol Chem. 1993 Feb 25;268(6):4259-66
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Thermodynamic characterization of the structural stability of the coiled-coil region of the bZIP transcription factor GCN4.
Biochemistry. 1993 Jun 1;32(21):5491-6
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Interactions of coiled coils in transcription factors: where is the specificity?
Curr Opin Genet Dev. 1993 Apr;3(2):278-85
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Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.
Genes Dev. 1993 Jun;7(6):1047-58
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C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.
Proc Natl Acad Sci U S A. 1993 May 15;90(10):4679-83
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A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants.
Science. 1993 Nov 26;262(5138):1401-7
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Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.
Mol Cell Biol. 1994 Jan;14(1):268-76
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Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins.
Nature. 1994 Feb 10;367(6463):568-72
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Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun.
Oncogene. 1994 Mar;9(3):675-84
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A thermodynamic scale for leucine zipper stability and dimerization specificity: e and g interhelical interactions.
EMBO J. 1994 Jun 15;13(12):2849-61
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Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.
Mol Cell Biol. 1994 Nov;14(11):7285-97
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MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.
Mol Cell Biol. 1994 Nov;14(11):7581-91
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A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins.
Oncogene. 1994 Nov;9(11):3149-58
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Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
Nature. 1995 Jan 19;373(6511):257-61
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The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides.
J Biol Chem. 1995 Mar 3;270(9):4387-94
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Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
Mol Cell Biol. 1995 Apr;15(4):2180-90
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The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability.
Protein Eng. 1994 Nov;7(11):1365-72
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Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element.
Mol Cell Biol. 1996 Apr;16(4):1479-89
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Coiled coils: new structures and new functions.
Trends Biochem Sci. 1996 Oct;21(10):375-82
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DNA-binding specificity of PAR and C/EBP leucine zipper proteins: a single amino acid substitution in the C/EBP DNA-binding domain confers PAR-like specificity to C/EBP.
Biol Chem. 1996 Dec;377(12):797-809
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Buried asparagines determine the dimerization specificities of leucine zipper mutants.
Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3673-8
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ATF-2 and C/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation.
J Biol Chem. 1997 May 9;272(19):12793-800
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The world according to Maf.
Nucleic Acids Res. 1997 Aug 1;25(15):2953-59
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A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis.
J Biol Chem. 1997 Jul 25;272(30):18586-94
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Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor.
Mol Cell Biol. 1997 Sep;17(9):5117-26
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Leucine is the most stabilizing aliphatic amino acid in the d position of a dimeric leucine zipper coiled coil.
Biochemistry. 1997 Oct 14;36(41):12567-73
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Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP.
Genes Dev. 1997 Dec 1;11(23):3122-7
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A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos.
Mol Cell Biol. 1998 Feb;18(2):967-77
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Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation.
Genes Dev. 1998 Apr 15;12(8):1227-39
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Inter-helical interactions in the leucine zipper coiled coil dimer: pH and salt dependence of coupling energy between charged amino acids.
J Mol Biol. 1998 Jun 19;279(4):959-72
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Cyclic AMP signaling and gene regulation.
Annu Rev Nutr. 1998;18:353-83
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A buried polar interaction can direct the relative orientation of helices in a coiled coil.
Biochemistry. 1998 Sep 8;37(36):12603-10
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