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PMID: 12015615 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

A small-systems approach to motor pattern generation.

Nature ·Vol. 417 ·No. 6886 ·2002-05-16 ·Pages 343-50

Nusbaum MP, Beenhakker MP

Abstract

How neuronal networks enable animals, humans included, to make coordinated movements is a continuing goal of neuroscience research. The stomatogastric nervous system of decapod crustaceans, which contains a set of distinct but interacting motor circuits, has contributed significantly to the general principles guiding our present understanding of how rhythmic motor circuits operate at the cellular level. This results from a detailed documentation of the circuit dynamics underlying motor pattern generation in this system as well as its modulation by individual transmitters and neurons.

MeSH Terms
Animals Crustacea/physiology Humans Membrane Potentials Models, Animal Nerve Net Nervous System Physiological Phenomena Neuronal Plasticity Neurons/cytology,physiology Synapses/physiology Synaptic Transmission
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Nusbaum Michael P
Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia 19104-6074, USA. msbaum@mail.med.upenn.edu
Beenhakker Mark P
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Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/417343a
Email
msbaum@mail.med.upenn.edu
Published
2002-05-16
Pages
343-50
Language
English
Region
England
NLM ID
0410462
PMCID
PMC6494453
Subset
IM
Grants
NINDS NIH HHS · R01 NS042813 · United States
External Links
PubMed source DOI: 10.1038/417343a PMC Full Text View journal details
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