Meiotic alterations in CAG repeat tracts.

Genetics ·Vol. 159 ·No. 4 ·2001-12-00 ·Pages 1861-5

Schweitzer JK, Reinke SS, Livingston DM

Abstract

We have investigated meiotic changes in CAG repeat tracts embedded in a yeast chromosome. Repeat tracts undergo either conversion events between homologs or expansion and contraction events that appear to be confined to a single chromatid. We did not find evidence for conversion of tract interruptions or excess exchange of flanking markers.

MeSH Terms

Chromosomes, Fungal Crosses, Genetic Crossing Over, Genetic Genes, Fungal Meiosis Models, Genetic Polymerase Chain Reaction Repetitive Sequences, Nucleic Acid Saccharomyces cerevisiae/genetics

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Schweitzer J K

Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Reinke S S

Livingston D M

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15 references, click to expand

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Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/159.4.1861

Published

2001-12-00

Pages

1861-5

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1461891

Subset

External Links

PubMed source DOI: 10.1093/genetics/159.4.1861 PMC Full Text View journal details

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