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PMID: 11675482 Published · ppublish English Comment Journal Article

Crosstalk of the group IIa and IIb metals calcium and zinc in cellular signaling.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 98 ·No. 22 ·2001-10-23 ·Pages 12325-7

Maret W

Abstract

暂无摘要

MeSH Terms
Animals Calcium/metabolism Humans Signal Transduction Type C Phospholipases/physiology Zinc/physiology
Chemicals
Type C Phospholipases Zinc Calcium
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Maret W
Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, Seeley G. Mudd Building, 250 Longwood Avenue, Boston, MA 02115, USA. wolfgang_maret@hms.harvard.edu
References (36)
36 references, click to expand
  1. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc.
    EMBO J. 1995 Feb 15;14(4):639-49 PMID: 7882967
  2. Intracellular free zinc and zinc buffering in human red blood cells.
    J Membr Biol. 1991 Jul;123(1):63-71 PMID: 1774775
  3. Zinc coordination, function, and structure of zinc enzymes and other proteins.
    Biochemistry. 1990 Jun 19;29(24):5647-59 PMID: 2200508
  4. Cadmium evokes inositol polyphosphate formation and calcium mobilization. Evidence for a cell surface receptor that cadmium stimulates and zinc antagonizes.
    J Biol Chem. 1989 May 5;264(13):7115-8 PMID: 2540174
  5. ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration.
    EMBO J. 1996 Apr 15;15(8):1784-91 PMID: 8617223
  6. Extracellular zinc ions induces mitogen-activated protein kinase activity and protein tyrosine phosphorylation in bombesin-sensitive Swiss 3T3 fibroblasts.
    Arch Biochem Biophys. 1996 Apr 15;328(2):233-8 PMID: 8644999
  7. ZnT-3, a putative transporter of zinc into synaptic vesicles.
    Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14934-9 PMID: 8962159
  8. Study of the interactions of cadmium and zinc ions with cellular calcium homoeostasis using 19F-NMR spectroscopy.
    Biochem J. 1997 Mar 15;322 ( Pt 3):793-9 PMID: 9148751
  9. A novel gene involved in zinc transport is deficient in the lethal milk mouse.
    Nat Genet. 1997 Nov;17(3):292-7 PMID: 9354792
  10. Thiolate ligands in metallothionein confer redox activity on zinc clusters.
    Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3478-82 PMID: 9520391
  11. Zinc and brain injury.
    Annu Rev Neurosci. 1998;21:347-75 PMID: 9530500
  12. Inhibitory sites in enzymes: zinc removal and reactivation by thionein.
    Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1936-40 PMID: 10051573
  13. Extracellular heavy-metal ions stimulate Ca2+ mobilization in hepatocytes.
    Biochem J. 1999 May 1;339 ( Pt 3):555-61 PMID: 10215593
  14. Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells.
    Am J Respir Cell Mol Biol. 1999 Sep;21(3):357-64 PMID: 10460753
  15. Zn2+ increases resting cytosolic Ca2+ levels and abolishes capacitative Ca2+ entry induced by ATP in MDCK cells.
    Naunyn Schmiedebergs Arch Pharmacol. 1999 Sep;360(3):249-55 PMID: 10543425
  16. Activation of the EGF receptor signaling pathway in human airway epithelial cells exposed to metals.
    Am J Physiol. 1999 Nov;277(5 Pt 1):L924-31 PMID: 10564177
  17. Cd2+ and Co2+ at micromolar concentrations stimulate catecholamine secretion by increasing the cytosolic free Ca2+ concentration in cat adrenal chromaffin cells.
    Brain Res. 1994 May 23;646(2):295-8 PMID: 8069676
  18. Transmembrane signals and protooncogene induction evoked by carcinogenic metals and prevented by zinc.
    Environ Health Perspect. 1994 Sep;102 Suppl 3:181-9 PMID: 7843095
  19. Excitation-transcription coupling mediated by zinc influx through voltage-dependent calcium channels.
    J Biol Chem. 1995 Feb 10;270(6):2473-7 PMID: 7852308
  20. The biochemical basis of zinc physiology.
    Physiol Rev. 1993 Jan;73(1):79-118 PMID: 8419966
  21. A novel dialysis procedure measuring free Zn2+ in bovine milk and plasma.
    J Nutr. 1995 Jul;125(7):1904-10 PMID: 7616307
  22. The galvanization of biology: a growing appreciation for the roles of zinc.
    Science. 1996 Feb 23;271(5252):1081-5 PMID: 8599083
  23. Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein.
    Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):477-82 PMID: 10618443
  24. Functional expression of the human hZIP2 zinc transporter.
    J Biol Chem. 2000 Feb 25;275(8):5560-4 PMID: 10681536
  25. Role of zinc in plasma membrane function.
    J Nutr. 2000 May;130(5S Suppl):1432S-6S PMID: 10801956
  26. Importance of zinc in the central nervous system: the zinc-containing neuron.
    J Nutr. 2000 May;130(5S Suppl):1471S-83S PMID: 10801962
  27. Zn(2+): a novel ionic mediator of neural injury in brain disease.
    Trends Pharmacol Sci. 2000 Oct;21(10):395-401 PMID: 11050320
  28. Zinc finger proteins: new insights into structural and functional diversity.
    Curr Opin Struct Biol. 2001 Feb;11(1):39-46 PMID: 11179890
  29. Zinc has an insulin-like effect on glucose transport mediated by phosphoinositol-3-kinase and Akt in 3T3-L1 fibroblasts and adipocytes.
    J Nutr. 2001 May;131(5):1414-20 PMID: 11340092
  30. Differential fluorescence labeling of cysteinyl clusters uncovers high tissue levels of thionein.
    Proc Natl Acad Sci U S A. 2001 May 8;98(10):5556-9 PMID: 11331777
  31. The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells.
    J Biol Chem. 2001 Jun 22;276(25):22258-64 PMID: 11301334
  32. A zinc-sensing receptor triggers the release of intracellular Ca2+ and regulates ion transport.
    Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11749-54 PMID: 11573009
  33. Regulation of phosphoinositide-specific phospholipase C.
    Annu Rev Biochem. 2001;70:281-312 PMID: 11395409
  34. Dietary metal-complexing agents and zinc availability in the rat.
    J Nutr. 1966 Sep;90(1):56-62 PMID: 4958459
  35. Metal complexes of phosphoglucomutase in vivo. Alterations induced by insulin.
    J Biol Chem. 1971 Feb 25;246(4):1160-7 PMID: 5543683
  36. The concentrations of free Mg2+ and free Zn2+ in equine blood plasma.
    J Biol Chem. 1987 Aug 15;262(23):11140-8 PMID: 2956262
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.231481398
Email
wolfgang_maret@hms.harvard.edu
Published
2001-10-23
Pages
12325-7
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC60047
Subset
IM
Corrections
CommentOn
PMID: 9520391
CommentOn
PMID: 10051573
CommentOn
PMID: 11331777
CommentOn
PMID: 11573009
External Links
PubMed source DOI: 10.1073/pnas.231481398 PMC Full Text View journal details
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