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PMID: 1101029 Published · ppublish English Journal Article

A new gene for ribosomal restriction in Escherichia coli.

Molecular & general genetics : MGG ·Vol. 137 ·No. 1 ·1975-00-00 ·Pages 73-78

Garvin RT, Gorini L

Abstract

Two mutations restricting the leakiness of an amber mutant are described. They were selected without the use of streptomycin: one maps in the strA region (at 64 minutes of the current E. coli chromosomal map) but is streptomycin sensitive and the other in the threonine region (at the origin of the map), 23% cotransducible with threonine by P1.

MeSH Terms
Chromosome Mapping Chromosomes, Bacterial Escherichia coli Genes Mutation/drug effects Ribosomes Streptomycin/pharmacology
Chemicals
Streptomycin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Garvin R T
Gorini L
References (10)
10 references, click to expand
  1. The contrasting role of strA and ram gene products in ribosomal functioning.
    Cold Spring Harb Symp Quant Biol. 1969;34:101-9 PMID: 4909486
  2. Kasugamycin resistance: 30S ribosomal mutation with an unusual location on the Escherichia coli chromosome.
    Science. 1970 Jan 2;167(3914):56-8 PMID: 4901406
  3. Alteration of ribosomal protein S4 by mutation linked to kasugamycin-resistance in Escherichia coli.
    Proc Natl Acad Sci U S A. 1973 Jan;70(1):71-5 PMID: 4567337
  4. Ribosomal discrimination of tRNAs.
    Nat New Biol. 1971 Dec 29;234(52):261-4 PMID: 4943838
  5. Alteration of a 30S ribosomal protein accompanying the ram mutation in Escherichia coli.
    Proc Natl Acad Sci U S A. 1971 Sep;68(9):2263-7 PMID: 4943794
  6. Change in methylation of 16S ribosomal RNA associated with mutation to kasugamycin resistance in Escherichia coli.
    Nat New Biol. 1971 Sep 1;233(35):12-4 PMID: 4329247
  7. A ribosomal ambiguity mutation.
    J Mol Biol. 1969 Jan 14;39(1):95-112 PMID: 4938819
  8. Electrophoretic and immunological studies on ribosomal proteins of 100 Escherichia coli revertants from streptomycin dependence.
    Mol Gen Genet. 1973 Dec 14;127(1):1-18 PMID: 4589343
  9. Transduction of linked genetic characters of the host by bacteriophage P1.
    Virology. 1955 Jul;1(2):190-206 PMID: 13267987
  10. Identification and functional characterization of the protein controlled by the streptomycin-resistant locus in E. coli.
    Nature. 1969 Apr 26;222(5191):333-9 PMID: 4181187
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
Published
1975-00-00
Pages
73-78
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
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