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PMID: 11002759 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

HTLV-1 infections.

Journal of clinical pathology ·Vol. 53 ·No. 8 ·2000-08-00 ·Pages 581-6

Bangham CR

Abstract

Human T lymphotropic virus type 1 (HTLV-1) causes disabling and fatal diseases, yet there is no vaccine, no satisfactory treatment, and no means of assessing the risk of disease or prognosis in infected people. Recent research on the molecular virology and immunology of HTLV-1 shows the importance of the host's immune response in reducing the risk of these diseases, and is beginning to explain why some HTLV-1 infected people develop serious illnesses whereas most remain healthy life long carriers of the virus. These findings might be applicable to other persistent virus infections such as human immunodeficiency virus, hepatitis B, and hepatitis C.

MeSH Terms
HLA-A2 Antigen/immunology HTLV-I Infections/immunology,virology Human T-lymphotropic virus 1/immunology Humans Leukemia-Lymphoma, Adult T-Cell/immunology Paraparesis, Tropical Spastic/immunology Proviruses/isolation & purification Viral Load
Chemicals
HLA-A2 Antigen
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Bangham C R
Department of Immunology, Imperial College School of Medicine, London, UK. c.bangham@ic.ac.uk
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Article Info
Journal
Journal of clinical pathology
Abbr.
J Clin Pathol
ISSN
0021-9746
DOI
10.1136/jcp.53.8.581
Email
c.bangham@ic.ac.uk
Published
2000-08-00
Pages
581-6
Language
English
Region
England
NLM ID
0376601
PMCID
PMC1762938
Subset
IM
External Links
PubMed source DOI: 10.1136/jcp.53.8.581 PMC Full Text View journal details
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