Home LiteratureArticle Details
PMID: 10809710 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Dual control of sbo-alb operon expression by the Spo0 and ResDE systems of signal transduction under anaerobic conditions in Bacillus subtilis.

Journal of bacteriology ·Vol. 182 ·No. 11 ·2000-06-00 ·Pages 3274-7

Nakano MM, Zheng G, Zuber P

Abstract

The Bacillus subtilis sbo-alb operon contains sboA, the structural gene for the bacteriocin subtilosin, and the alb genes required for subtilosin production. Transcription from the sbo-alb promoter is highly induced by oxygen limitation. The transcriptional regulation of the sbo-alb operon is under dual control involving the transition state regulator AbrB and the two-component regulatory proteins ResD and ResE.

MeSH Terms
Anaerobiosis Anti-Bacterial Agents/biosynthesis Bacillus subtilis/genetics Bacterial Proteins/metabolism Bacteriocins/biosynthesis Base Sequence DNA-Binding Proteins/metabolism Gene Expression Regulation, Bacterial Histidine Kinase Molecular Sequence Data Operon Peptides Peptides, Cyclic Protein Kinases/metabolism Sigma Factor Signal Transduction Transcription Factors/metabolism
Chemicals
AbrB protein, Bacillus subtilis Anti-Bacterial Agents Bacterial Proteins Bacteriocins DNA-Binding Proteins Peptides Peptides, Cyclic ResD protein, Bacillus subtilis Sigma Factor Transcription Factors spoIIR protein, Bacillus subtilis spore-specific proteins, Bacillus sboA protein, Bacillus subtilis Protein Kinases Histidine Kinase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Nakano M M
Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and Technology, Beaverton, Oregon 97006, USA.
Zheng G
Zuber P
References (30)
30 references, click to expand
  1. Characterization of the gene for a protein kinase which phosphorylates the sporulation-regulatory proteins Spo0A and Spo0F of Bacillus subtilis.
    J Bacteriol. 1989 Nov;171(11):6187-96 PMID: 2509430
  2. Pho signal transduction network reveals direct transcriptional regulation of one two-component system by another two-component regulator: Bacillus subtilis PhoP directly regulates production of ResD.
    Mol Microbiol. 1998 Dec;30(5):943-53 PMID: 9988472
  3. A physiological role for DNA supercoiling in the anaerobic regulation of colicin gene expression.
    Mol Gen Genet. 1991 Feb;225(2):342-5 PMID: 2005875
  4. Transcription initiation region of the srfA operon, which is controlled by the comP-comA signal transduction system in Bacillus subtilis.
    J Bacteriol. 1991 Sep;173(17):5487-93 PMID: 1715856
  5. Anaerobic control of colicin E1 production.
    J Bacteriol. 1992 Aug;174(15):5101-9 PMID: 1629167
  6. Integration of multiple developmental signals in Bacillus subtilis through the Spo0A transcription factor.
    Genes Dev. 1993 Feb;7(2):283-94 PMID: 8436298
  7. Regulation of peptide antibiotic production in Bacillus.
    Mol Microbiol. 1993 Mar;7(5):631-6 PMID: 7682277
  8. Multisensory activation of the phosphorelay initiating sporulation in Bacillus subtilis: identification and sequence of the protein kinase of the alternate pathway.
    Mol Microbiol. 1993 Apr;8(1):69-79 PMID: 8497199
  9. Isolation and characterization of kinC, a gene that encodes a sensor kinase homologous to the sporulation sensor kinases KinA and KinB in Bacillus subtilis.
    J Bacteriol. 1995 Jan;177(1):166-75 PMID: 8002614
  10. Different roles for KinA, KinB, and KinC in the initiation of sporulation in Bacillus subtilis.
    J Bacteriol. 1995 Feb;177(3):861-3 PMID: 7836330
  11. The anaerobic life of Bacillus subtilis: cloning of the genes encoding the respiratory nitrate reductase system.
    FEMS Microbiol Lett. 1995 Sep 1;131(2):219-25 PMID: 7557333
  12. Anaerobic transcription activation in Bacillus subtilis: identification of distinct FNR-dependent and -independent regulatory mechanisms.
    EMBO J. 1995 Dec 1;14(23):5984-94 PMID: 8846791
  13. Regulators of aerobic and anaerobic respiration in Bacillus subtilis.
    J Bacteriol. 1996 Mar;178(5):1374-85 PMID: 8631715
  14. Two-component regulatory proteins ResD-ResE are required for transcriptional activation of fnr upon oxygen limitation in Bacillus subtilis.
    J Bacteriol. 1996 Jul;178(13):3796-802 PMID: 8682783
  15. When the going gets tough: survival strategies and environmental signaling networks in Bacillus subtilis.
    Trends Microbiol. 1999 May;7(5):201-7 PMID: 10354595
  16. Alanine mutants of the Spo0F response regulator modifying specificity for sensor kinases in sporulation initiation.
    Mol Microbiol. 1999 Jul;33(2):389-95 PMID: 10411754
  17. Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin.
    J Bacteriol. 1999 Dec;181(23):7346-55 PMID: 10572140
  18. Increased nitrate reductase A activity as a sign of membrane alteration in early blocked asporogenous mutants of Bacillus subtilis.
    Biochimie. 1976;58(1-2):99-108 PMID: 821543
  19. The peptide antibiotics of Bacillus: chemistry, biogenesis, and possible functions.
    Bacteriol Rev. 1977 Jun;41(2):449-74 PMID: 70202
  20. Subtilosin A, a new antibiotic peptide produced by Bacillus subtilis 168: isolation, structural analysis, and biogenesis.
    J Biochem. 1985 Sep;98(3):585-603 PMID: 3936839
  21. Identification of a genetic locus required for biosynthesis of the lipopeptide antibiotic surfactin in Bacillus subtilis.
    J Bacteriol. 1988 Dec;170(12):5662-8 PMID: 2848009
  22. Oxygen-controlled regulation of the flavohemoglobin gene in Bacillus subtilis.
    J Bacteriol. 1996 Jul;178(13):3803-8 PMID: 8682784
  23. Genetic networks controlling the initiation of sporulation and the development of genetic competence in Bacillus subtilis.
    Annu Rev Genet. 1995;29:477-508 PMID: 8825484
  24. Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria.
    Mol Microbiol. 1997 Jun;24(5):895-904 PMID: 9219998
  25. Characterization of anaerobic fermentative growth of Bacillus subtilis: identification of fermentation end products and genes required for growth.
    J Bacteriol. 1997 Nov;179(21):6749-55 PMID: 9352926
  26. The complete genome sequence of the gram-positive bacterium Bacillus subtilis.
    Nature. 1997 Nov 20;390(6657):249-56 PMID: 9384377
  27. Nitrogen and oxygen regulation of Bacillus subtilis nasDEF encoding NADH-dependent nitrite reductase by TnrA and ResDE.
    J Bacteriol. 1998 Oct;180(20):5344-50 PMID: 9765565
  28. A vector for systematic gene inactivation in Bacillus subtilis.
    Microbiology. 1998 Nov;144 ( Pt 11):3097-104 PMID: 9846745
  29. Anaerobic growth of a "strict aerobe" (Bacillus subtilis).
    Annu Rev Microbiol. 1998;52:165-90 PMID: 9891797
  30. The SpoOA protein of Bacillus subtilis is a repressor of the abrB gene.
    Proc Natl Acad Sci U S A. 1990 Mar;87(5):1801-5 PMID: 2106683
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/JB.182.11.3274-3277.2000
Published
2000-06-00
Pages
3274-7
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC94517
Subset
IM
Grants
NIGMS NIH HHS · R01 GM045898 · United States
NIGMS NIH HHS · GM45898 · United States
External Links
PubMed source DOI: 10.1128/JB.182.11.3274-3277.2000 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2