XAGE1C (X antigen family, member 1C)
- symbol:
- XAGE1C
- locus group:
- protein-coding gene
- location:
- Xp11.22
- gene_family:
- alias symbol:
- CT12.1c
- alias name:
- cancer/testis antigen family 12, m…
- entrez id:
- 653048
- ensembl gene id:
- ucsc gene id:
- refseq accession:
- hgnc_id:
- HGNC:30679
- approved reserved:
- 2006-06-30T00:00:00Z
None
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]
该基因是XAGE亚科，属于GAGE家族的一员。的GAGE基因在多种肿瘤，并在一些胎儿和生殖组织中表达。此基因在尤文肉瘤，肺泡横纹肌肉瘤和正常睾丸中强烈表达。由该基因编码的蛋白质包含核定位信号和共享与其他GAGE / PAGE的蛋白质的序列相似性。因为表达模式和序列相似性，这种蛋白也属于一个家族的CT（癌 - 睾丸）抗原。该基因的选择性剪接，除了替代转录起始位点，结果在多个抄本变形。 [由RefSeq的，2010年1月提供]
基因本体信息
XAGE1C基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
XAGE1C基因的本体（GO）信息：
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