TSPAN2 (tetraspanin 2)
- symbol:
- TSPAN2
- locus group:
- protein-coding gene
- location:
- 1p13.2
- gene_family:
- Tetraspanins
- alias symbol:
- TSPAN-2|TSN2|FLJ12082
- alias name:
- None
- entrez id:
- 10100
- ensembl gene id:
- ENSG00000134198
- ucsc gene id:
- uc001eft.5
- refseq accession:
- NM_005725
- hgnc_id:
- HGNC:20659
- approved reserved:
- 2005-01-06
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
由该基因编码的蛋白是跨膜4超家族的成员，也称为四旋家族。大多数这些成员是细胞表面蛋白质的特征在于四个疏水区的存在。蛋白质介导其在细胞发育，活化，生长和运动的调节作用的信号转导事件。在多个转录剪接变异体导致编码不同亚型。 [由RefSeq的，2015年4月提供]
基因本体信息
TSPAN2基因（以及对应的蛋白质）的细胞分布位置：
- 质膜
- 细胞质
- 细胞外
- 高尔基体
- 囊泡
- 细胞骨架
- 内质网
- 细胞核
- 内体
- 溶酶体
- 线粒体
TSPAN2基因的本体（GO）信息：
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Alcoholic Intoxication, Chronic | 0.002367032 | 1 | 1 | GAD |
| Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
| Neoplasm Metastasis | 0.000542884 | 2 | 0 | BeFree |
| Migraine Disorders | 0.000542884 | 2 | 6 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
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